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What we learned in NFL Week 2: Chiefs face uphill climb, Bengals hold their breath

Is it time to panic in Kansas City? Not even close. But the Chiefs are suddenly somewhere they’ve never been in the Patrick Mahomes era: winless two weeks into the season. And Mahomes, dating back to February’s Super Bowl, has now dropped three straight games for the first time since he was a junior at Texas Tech.
The Philadelphia Eagles gutted out a 20-17 win in Sunday’s Super Bowl rematch, sealing the victory late with a slew of Tush Pushes, including a touchdown from Jalen Hurts midway through the fourth quarter. But Philly, now 2-0, can largely thank its defense for this one: The Chiefs converted just four third-downs all game and Mahomes managed only 187 passing yards. The result also continued the NFL’s trend surrounding Super Bowl rematches the following season: Of the six times it’s happened this century, five have gone to the reigning world champs.
Same as Week 1, late-game drama ruled the second week of the 2025 NFL season. The Dallas Cowboys and New York Giants staged a 77-point overtime thriller. The Denver Broncos cost themselves a win with a penalty on what would’ve been the game’s final snap. The New England Patriots and Miami Dolphins exchanged kick return touchdowns on consecutive plays.
But the biggest news came out of Cincinnati, where the Bengals lost quarterback Joe Burrow for what could be a while.
In Indianapolis, the Broncos’ elation dissolved into disbelief after what appeared to be a last-second win over the Colts — thanks to Indy kicker Spencer Shrader pushing a 60-yard field goal wide right as time expired — instead became a cruel lesson in the intricacies of the NFL rulebook.
While some Broncos celebrated Shrader’s miss, Denver coach Sean Payton learned why there was a flag on the field: His team was being called for a leverage penalty after linebacker Dondrea Tillman used his left hand to jump off the back of Colts lineman Dalton Tucker. The league’s rulebook defines leverage as “a defensive player jumping or standing on a teammate or an opponent to block or attempt to block an opponent’s kick.” The violation was called just four times last season. On Sunday, it cost the Broncos a victory.
Because, given another opportunity from 15 yards closer, Shrader nailed it. Colts 29, Broncos 28.
“We did a lot of things late in that game to keep us from winning,” Payton said. “It will be painful to watch that film.”
The Colts are now 2-0 for the first time since 2009, the last time they reached the Super Bowl. More impressively, Indy is now is the only team of the Super Bowl era — which dates back to 1967 —to not punt in either of its first two games of a season.
In Miami, the Dolphins slumped to 0-2 after dropping a wild back-and-forth contest with the Patriots that featured four second-half lead changes. How chaotic was this one? Weigh this sequence, midway through the fourth quarter: Miami return man Malik Washington took a punt 74 yards to the house to give the Dolphins the lead, only to watch Patriots returner Antonio Gibson answer with a 90-yard kickoff return of his own that put New England back in front. It was the first time since 2008 that a game featured a punt or kick return for a touchdown on consecutive plays.
In the end, it was Milton Williams, the Patriots’ new $104-million defensive tackle, who sealed the 33-27 victory with a sack of Dolphins quarterback Tua Tagovailoa. Sunday’s win — the first for Mike Vrabel in New England — was also the first time the Patriots scored more than 30 points in a game since October 2022.
In Tennessee, the Los Angeles Rams’ Davante Adams had a vintage day for his new team — six catches for 106 yards and a touchdown — in a 33-19 victory over the Titans. Top pick Cam Ward had his moments, including a wild scramble that preceded an incredible against-his-body touchdown throw to Elic Ayomanor in the second quarter, but the Los Angeles defense proved too much in the second half. Ward was sacked five times as the Titans fell to 0-2. The Rams are now 2-0 for the first time since their Super Bowl year of 2021.
In Baltimore, the Ravens shook off last week’s stunning loss to the Bills by stomping the Cleveland Browns 41-17. The defense responded, limiting Joe Flacco to a 25-for-45, two-turnover stat line in his Baltimore homecoming. By the fourth quarter, Flacco was out and rookie Dillon Gabriel was getting his first NFL snaps.
In New Orleans, the 49ers led from start to finish in a 26-21 win over the Saints that pushed San Francisco to 2-0. In Brock Purdy’s stead, Mac Jones stepped in and threw three touchdowns, and Christian McCaffrey — the recipient of one of those touchdowns — became just the third player in NFL history with 50 rushing scores and 30 receiving scores, joining Hall of Famers Marshall Faulk and Lenny Moore.
At MetLife Stadium in New Jersey, the reigning MVP overcame a nasty shot to the nose that left him bleeding and sidelined for a few snaps. No matter, Josh Allen and the Bills dominated the Jets, 30-10, to move to 2-0. Buffalo’s defense was stifling, holding the Jets to just 87 yards through three quarters. A week after an encouraging offensive performance, New York (now 0-2) regressed in a big way — Justin Fields was 3-for-11 for 27 yards before leaving the game early in the fourth quarter to be evaluated for a concussion.
In Seattle, Pittsburgh Steelers rookie Kaleb Johnson learned a valuable lesson: If you muff a kickoff, don’t assume the ball is going to bounce out of bounds. Johnson’s gaffe — which came with 12:46 left in the game and the Steelers down three — cost his team dearly. The ball hung in the back of the end zone before Seattle’s George Holani recovered it for a touchdown, pushing the Seahawks’ lead to double digits. It was a momentum swing the Steelers never recovered from in a 31-17 loss to the Seahawks.
“Poor judgment by a young player,” was how coach Mike Tomlin put it.
Aaron Rodgers, fresh off a four-touchdown game in his Steelers debut, finished 18-for-33 for 203 yards, a touchdown and two interceptions. Both teams are now 1-1.
In Arizona, the Cardinals improved to 2-0 with a 27-22 win over the Panthers. Arizona dominated this one early, then used a sack from the ageless Calais Campbell — he’s in his 18th season — to seal it late. For the first time in the Jonathan Gannon era, the Cardinals are undefeated after two weeks, and for the fourth straight year, the Panthers are 0-2.
Here’s what stood out from Week 2 of the NFL season:
These aren’t the Chiefs we know
Some hard truths about this version of the Chiefs:
They can’t run the football. Kansas City running backs combined for 57 yards in a Week 1 loss to the Chargers, then just 55 on Sunday. The leading rusher in each game? Mahomes.
They can’t protect the quarterback, especially on the right side. Mahomes was hit eight times in the opener and 10 times Sunday.
Their offense, outside their all-world quarterback, doesn’t scare anybody, not without Rashee Rice (suspension) and Xavier Worthy (injury), and with Travis Kelce in Year 13. The tight end could’ve made the play of the game early in the fourth quarter, but he badly bobbled Mahomes’ pass on the goal line, leading to an interception and 41-yard return for Eagles rookie Drew Mukuba.
So, instead of surging to a 17-13 lead, the Chiefs’ offense watched Jalen Hurts and the Eagles Tush Push their way to victory.
It’s the middle of September, and the Chiefs are not your typical 0-2 team. They’ve played in the last three Super Bowls. They won two of them. Mahomes is still under center. Andy Reid is still coaching. The defense responded well Sunday after last week’s ugly loss to the Chargers.
In all likelihood, this team will right the ship soon.
But the road back is getting bumpier, and the AFC West might be the deepest division in football. Until KC unlocks something on offense, this season might more of a grind than this team’s used to.
For now, the odds are against them: since the playoffs expanded in 2020, teams that start 0-2 qualified for the postseason just 12 percent of the time (5 of 41). And only two Super Bowl champs since 2000 — the 2001 Patriots and 2007 Giants — opened the season with consecutive losses.
Bengals win, now they wait
It’s the image Bengals fans most fear: Joe Burrow limping off the field in pain.
It arrived again Sunday, in the second quarter of a 31-27 victory over the Jaguars. Cincinnati’s franchise quarterback remained on the ground after a sack by Jaguars defensive lineman Arik Armstead, then pointed at his left foot as members of the Bengals medical staff attended to him.
The likely diagnosis: turf toe. The impact: yet to be determined. The Bengals go as Burrow goes, and a looming absence — if surgery is required, Burrow could be out multiple months — would reshape Cincinnati’s aim of returning to the playoffs.
But all was not lost. Burrow’s backup, Jake Browning, proved his mettle, overcoming three interceptions to lead a 92-yard game-winning drive late in the fourth. The Jaguars were hurt late by a bold fourth-down call from first-year coach Liam Coen, a drop from Brian Thomas Jr. and a pass interference penalty from Travis Hunter. Cincinnati won the game despite not leading until 18 seconds remained.
“Today I saw the most resilient team I’ve ever seen,” an ebullient Bengals coach Zac Taylor told his players in the locker room.
At least Browning has experience in this spot: he went 4-3 as the team’s starter in 2023 while Burrow was sidelined with a wrist injury. And he won’t be digging the Bengals out of a hole. Cincinnati started 0-2 or worse in five of Taylor’s first six seasons. This year, the Bengals are 2-0.
McCarthy can’t replicate Week 1 heroics
This wasn’t exactly the Sunday nighter of a week ago, an all-time Bills comeback over the Ravens.
And it wasn’t anything close to how the Minnesota Vikings’ J.J. McCarthy closed the first start of his NFL career, with a fourth-quarter comeback over the Chicago Bears that included three touchdowns across the final 12 minutes.
Sunday night’s 22-6 Falcons victory leaves both teams 1-1. Credit Atlanta, which leaned on five field goals from new kicker Parker Romo before scoring the game’s first touchdown late in the fourth quarter. Bijan Robinson, with 143 yards, was the best offensive player on the field. The Falcons’ defense was excellent, finishing with six sacks, two interceptions and three forced fumbles.
McCarthy struggled throughout, missing too many throws, including some big chances in the second half. He’s now played eight quarters in the NFL. One has been terrific. Seven have been lousy. The Vikings’ offense finished with just 198 yards. McCarthy finished with a passer rating of 37.5. That’s life for a young quarterback in the NFL.
Campbell, Lions make their statement
All week, the chatter in Detroit centered on what the Lions were missing — specifically who the Lions were missing. The offense didn’t look right in their season-opening loss in Green Bay, Detroit’s first game without Ben Johnson calling the plays in three years. Coach Dan Campbell fielded questions about why the scheme didn’t look the same and why it didn’t perform the same. Were the Lions still the Lions without their star offensive coordinator? Or was Johnson really the driving force behind 27 regular-season wins over the last two years and back-to-back NFC North titles?
Even one week into the season, the pressure seemed real. Especially on Campbell, who was facing Johnson — the new head coach of the Bears — for the first time.
“We’re going to win this game,” Campbell predicted. “We have to.”
They did in resounding fashion, bullying Johnson and the Bears all afternoon and pouring it on in a 52-21 rout.
“It’s like they forgot that we’re fighters,” Campbell told his team in the locker room.
Jared Goff threw five touchdowns. Amon-Ra St. Brown caught three of them. Jameson Williams had another. Jahmyr Gibbs and David Montgomery combined for 151 rushing yards and two scores. This was Detroit at its best — and Campbell’s team offering a reminder that it’s not going anywhere.
Cowboys, Giants stage a thriller
A week after that Sunday night classic in Buffalo, we have another nominee for Game of the Year: Sunday’s Cowboys-Giants game was utterly absurd. The two teams combined for 41 fourth-quarter points, including 17 in the final 52 seconds of regulation. They exchanged leads six times in the final quarter and overtime — the most in NFL history. Quarterbacks Russell Wilson and Dak Prescott threw for 811 passing yards. And the Cowboys somehow found a way to eke out a 40-37 overtime victory to avoid an 0-2 start to the season.
Prescott was asked afterwards the difference between 1-1 and 0-2.
“Sh—, I don’t want to know,” he laughed.
Wilson, after a dismal season-opener last week in which he threw for just 168 yards in a loss to the Commanders, erupted for 450 on Sunday, his most in a game since 2017. But a costly interception in overtime set up the fourth field goal of the day from Cowboys kicker Brandon Aubrey, who was good from 46 to win it. Aubrey — one of the very best in the league — had drilled a 64-yarder as regulation expired to force overtime.
“We’re thankful for that guy,” Prescott said of his kicker.
All of which secured Brian Schottenheimer’s first win as Cowboys coach and Prescott’s 14th straight victory over the Giants. New York — after looking lifeless a week ago in Washington — showed plenty of fight Sunday, which makes the defeat all the more gutting. The Giants are now 0-2 for the seventh time in the last nine seasons.
(Photo: David Eulitt / Getty Images)
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Texans vs. Buccaneers prediction, odds, time: 2025 NFL Week 2 Monday Night Football picks from proven model

A double dose of ‘Monday Night Football’ kicks off with C.J. Stroud and the Houston Texans hosting Baker Mayfield and the Tampa Bay Buccaneers. The hosts are looking for their first win of the 2025 NFL season after stumbling in Week 1 against the Los Angeles Rams 14-9. Meanwhile, the Buccaneers head into NFL Week 2 with a victory under their belts, having held off the Atlanta Falcons 23-20 to start their season. Both teams will be missing a key receiver with Christian Kirk (hamstring) out for Houston and Chris Godwin (foot) out for Tampa Bay.
Kickoff from NRG Stadium is set for 7 p.m. ET. Houston is a 2.5-point favorite in the latest Buccaneers vs. Texans odds, and the over/under for total points scored is 42.5. The Texans are -146 favorites on the money line (risk $146 to win $100), while the Bucs are +122 underdogs (risk $100 to win $122). Before making any Texans vs. Buccaneers picks, be sure to see what the SportsLine projection model has to say.
New users can also target the DraftKings promo code, which offers $200 in bonus bets instantly plus over $200 off NFL Sunday Ticket:
The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model is on a 33-17 run on top-rated picks dating back to 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns.
Now, the model has zeroed in on Texans vs. Buccaneers. You can head to SportsLine now to see its picks. Here are several NFL odds and betting lines for Buccaneers vs. Texans:
Buccaneers vs. Texans spread |
Texans -2.5 at DraftKings Sportsbook |
Buccaneers vs. Texans over/under |
42.5 points |
Buccaneers vs. Texans money line |
Houston -146, Tampa Bay +122 |
Buccaneers vs. Texans picks |
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Buccaneers vs. Texans streaming |
Fubo (Try for free) |
Why the Buccaneers can cover
The Bucs went 10-7-0 ATS last season and have already covered the spread in their first game of the season. They were arguably lucky to get the win in Week 1 since they didn’t generate much yardage, but Mayfield still threw three touchdown passes and rookie receiver Emeka Egbuka shined by catching two of those TDs. Egbuka can help open up the offense by taking some of the attention off of Mike Evans, giving Mayfield options against a Texans defense that allowed 244 passing yards in Week 1. See which team to back at SportsLine.
Why the Texans can cover
Houston is in a position to rebound after Ka’imi Fairbairn scored all of its Week 1 points with three first-half field goals. Nico Collins can have a bounce-back game by frustrating a Buccaneers defense that allowed the fourth-most passing yards in Week 1 (289 out of 358 yards total). Nick Chubb had 13 carries for 60 yards against the Rams, so he should be firing on all cylinders in his first home game with the Texans. Houston was 7-8-2 ATS in 2024 and covered four times at home. See which team to back at SportsLine.
New users can also check out the latest FanDuel promo code and get $300 in bonus bets instantly at FanDuel if your $5 bet wins.
How to make Texans vs. Buccaneers picks
For this NFL Week 2 Monday Night Football game, the model is leaning over the total, and also says one side of the spread hits almost 60% of the time. See what it is at SportsLine.
Who wins Buccaneers vs. Texans, and which side of the spread hits almost 60% of the time? Visit SportsLine now to see which side of the Texans vs. Buccaneers spread you need to jump, all from the model that is 33-17 on top-rated picks since 2024, and find out.
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5 new members for CDC’s Advisory Committee on Immunization Practices : Shots

The CDC’s Advisory Committee on Immunization Practice will have five additional members when it convenes Thursday in Atlanta.
Ben Hendren/Bloomberg via Getty Images
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Ben Hendren/Bloomberg via Getty Images
Just days before vaccine advisers to the Centers for Disease Control and Prevention meet to weigh who should get COVID vaccines this season, Health Secretary Robert F. Kennedy Jr. has selected five more members to the committee he purged of Biden administration appointees in June.
The new members of the influential Advisory Committee on Immunization Practices are:
- Hilary Blackburn, a pharmacist at AscensionRx, who also hosts a podcast,
- Dr. Kirk Milhoan, a pediatric cardiologist and an affiliate of the Independent Medical Alliance,
- Dr. Evelyn Griffin, an ob/gyn and functional medicine practitioner,
- Dr. Raymond Pollak, a semi-retired transplant surgeon, and
- Catherine Stein, an epidemiology professor at Case Western Reserve University, who has claimed the government overstated COVID risks.
“The new ACIP members bring a wealth of real-world public health experience to the job of making immunization recommendations,” said Jim O’Neill, Deputy Secretary of Health and Human Services and Acting Director of the CDC in a media statement. “We are grateful for their service in helping restore the public confidence in vaccines that was lost during the Biden era.”
The advisory group – now numbering 12 members – makes recommendations that help determine which vaccines are offered free through the Vaccines for Children program, and what health insurers typically cover. They also influence state and local laws around vaccine requirements.
The appointments expand the committee just before it meets this week in Atlanta. On Thursday and Friday, the members will be considering policies such as who should get the fall COVID-19 booster shot, and whether all babies should get the hepatitis B vaccine at birth.
Short list of members leaked in early September
The new members were among seven that appeared on a list that was first reported by the “Inside Medicine” newsletter on Sept. 3. Two others who were named then — Dr. Joseph Fraiman, an emergency medical physician, and Dr. John Gaitanis, a pediatric neurologist at Hasbro Children’s Hospital in Rhode Island — were not appointed to the committee by HHS.
NPR reached out to each of the new members of the committee earlier this month, when their names first appeared in media reports. Only one responded.
Dr. Raymond Pollak, a semi-retired transplant surgeon, was still in the midst of the vetting process on Sept. 5. “I think I’d be an ideal choice for a committee like this,” he told NPR. “I have expertise in clinical trial management and ethics, and my background in transplant biology allows me to understand the science of what is being proposed.”
Pollak says he had not paid much attention to ACIP before he joined the committee, but he sees having non-vaccine experts on the panel as a plus. “I think it’s a value to have broad representation of the community at large, both with and without the necessary expertise in order to formulate policy that makes sense to everybody,” he says.
And while Pollack considers COVID vaccines “safe to administer and provided a benefit in that it kept down the severity of the illness and prevented hospitalization,” he says the vaccine rollout was “poorly managed,” contributing to hysteria and conspiracy theories that the government covered up harms and injuries related to the vaccine. “The notion that the government tried to ‘cover it up’ is false,” Pollak says. “All of the information on adverse effects is readily available in the medical literature. The problem is it tends to stay within the profession and doesn’t get disseminated widely amongst the public.”
Kennedy’s imprint on vaccine panel grows
The new members join the seven others Kennedy named to the panel in June, replacements he handpicked after firing all 17 of the panel’s previously seated members. The replacements, who met for the first time at the CDC in June, include Dr. Robert Malone, who has spread misinformation about COVID and opposed vaccine mandates, and Retsef Levi, an MIT professor of operations management who gained prominence during the pandemic for criticizing COVID vaccines.
The members Kennedy fired had been chosen for their medical expertise and understanding of vaccine policy, and had been formally vetted to ensure that they would not directly financially benefit from any ACIP votes. They had been serving in overlapping rotations over several years to ensure continuity of expertise and process.
“There are large gaps in the new ACIP’s composition in terms of their missing expertise on vaccinology, their missing expertise on primary care, their missing expertise on cost effectiveness and clinical trials,” says Noel Brewer, a former ACIP member who had served on the committee for a year before being dismissed by Kennedy in June. “These are folks who fundamentally do not understand vaccines in a deep way. I wouldn’t take medical advice from them, and I certainly don’t think they should be setting policy for the United States.”
Since Kennedy overhauled the panel, the ACIP has seen major changes to how it operates, for instance voting to effectively ban flu vaccines with the mercury-containing preservative thimerosal in their June meeting. The change was based on debunked claims without new scientific evidence of harms. This move, among others, has led top medical organizations and public health groups to question the integrity of the group’s advice.
“Misinformation, politicization of commonsense public health efforts, and sudden changes to federal vaccine guidance is creating mass confusion and diminishing trust in public health. As we head into another fall season sure to be marked by cases of flu, Covid-19, and RSV as well as the alarming reappearance of measles and pertussis, the stakes could not be higher,” the presidents of five professional medical groups, including the American Academy of Pediatrics and the American College of Physicians wrote, in a June op-ed in Stat News.
Many state vaccine laws are tied to ACIP guidance. Some states led by Democratic governors are starting to reduce their reliance on the committee over concerns that future recommendations may be based on “ideology and not science,” says Dennis Worsham, health secretary for the Washington State Department of Health, which has formed a vaccine policy alliance with California, Oregon and Hawaii.
Rob Stein contributed to this report
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