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Weedkiller ingredient widely used in US can damage organs and gut bacteria, research shows | Herbicides

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The herbicide ingredient used to replace glyphosate in Roundup and other weedkiller products can kill gut bacteria and damage organs in multiple ways, new research shows.

The ingredient, diquat, is widely employed in the US as a weedkiller in vineyards and orchards, and is increasingly sprayed elsewhere as the use of controversial herbicide substances such as glyphosate and paraquat drops in the US.

But the new piece of data suggests diquat is more toxic than glyphosate, and the substance is banned over its risks in the UK, EU, China and many other countries. Still, the EPA has resisted calls for a ban, and Roundup formulas with the ingredient hit the shelves last year.

“From a human health perspective, this stuff is quite a bit nastier than glyphosate so we’re seeing a regrettable substitution, and the ineffective regulatory structure is allowing it,” said Nathan Donley, science director with the Center For Biological Diversity, which advocates for stricter pesticide regulations but was not involved in the new research. “Regrettable substitution” is a scientific term used to describe the replacement of a toxic substance in a consumer product with an ingredient that is also toxic.

Diquat is also thought to be a neurotoxin, carcinogen and linked to Parkinson’s disease. An October analysis of EPA data by the Friends of the Earth non-profit found it is about 200 times more toxic than glyphosate in terms of chronic exposure.

Bayer, which makes Roundup, faced nearly 175,000 lawsuits alleging that the product’s users were harmed by the product. Bayer, which bought Monsanto in 2018, reformulated Roundup after the International Agency for Research on Cancer classified glyphosate as a possible carcinogen.

The new review of scientific literature in part focuses on the multiple ways in which diquat damages organs and gut bacteria, including by reducing the level of proteins that are key pieces of the gut lining. The weakening can allow toxins and pathogens to move from the stomach into the bloodstream, and trigger inflammation in the intestines and throughout the body. Meanwhile, diquat can inhibit the production of beneficial bacteria that maintain the gut lining.

Damage to the lining also inhibits the absorption of nutrients and energy metabolism, the authors said.

The research further scrutinizes how the substance harms the kidneys, lungs and liver. Diquat “causes irreversible structural and functional damage to the kidneys” because it can destroy kidney cells’ membranes and interfere with cell signals. The effects on the liver are similar, and the ingredient causes the production of proteins that inflame the organ.

Meanwhile, it seems to attack the lungs by triggering inflammation that damages the organ’s tissue. More broadly, the inflammation caused by diquat may cause multiple organ dysfunction syndrome, a scenario in which organ systems begin to fail.

The authors note that many of the studies are on rodents and more research on low, long-term exposure is needed. Bayer did not immediately respond to a request for comment.

Despite the risks amid a rise in diquat’s use, the EPA is not reviewing the chemical, and even non-profits that push for tighter pesticide regulations have largely focused their attention elsewhere.

Donley said that was in part because US pesticide regulations are so weak that advocates are tied up with battles over ingredients like glyphosate, paraquat and chlorpyrifos – substances that are banned elsewhere but still widely used here. Diquat is “overshadowed” by those ingredients.

“Other countries have banned diquat, but in the US we’re still fighting the fights that Europe won 20 years ago,” Donley said. “It hasn’t gotten to the radar of most groups and that really says a lot about the sad and sorry state of pesticides in the US.”

Some advocates have accused the EPA of being captured by industry, and Donley said US pesticide laws were so weak that it was difficult for the agency to ban ingredients, even if the will exists. For example, the agency banned chlorpyrifos in 2022, but a court overturned the decision after industry sued.

Moreover, the EPA’s pesticides office seems to have a philosophy that states that toxic pesticides are a “necessary evil”, Donley said.

“When you approach an issue from that lens there’s only so much you will do,” he said.



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Children’s camps in Texas were located in areas known to be at high risk of flooding

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The waterways in Texas Hill Country have carved paths over the centuries through the granite and limestone, shaping the rocky peaks and valleys that make the region so breathtaking.

When too much rain falls for the ground to absorb, it runs downhill, pulled by gravity into streams, creeks and rivers. The rain fills the waterways beyond their banks, and the excess overflows in predictable patterns that follow the terrain.

Governments and waterway managers know what will flood first and who will be threatened when a truly historic rain event takes place.

Several of the camps along the Guadalupe River and its tributaries sustained damage early July 4. Many of them are in areas known to flood.

The Federal Emergency Management Agency maintains a database of flood zones throughout the country. It maps the regulatory floodways — the places that will flood first and are most dangerous — and the areas that will flood in extreme events.

The Guadalupe River flood was a 1-in-100-year event, meaning it has about a 1% chance of happening in any given year. Extreme flooding is happening more frequently as the world warms and the atmosphere is able to hold more moisture.

Texas has already seen multiple dangerous flooding events this year, and the United States overall saw a record number of flash flood emergencies last year.

More than an entire summer’s worth of rain fell in some spots in central Texas in just a few hours early on the Fourth of July, quickly overwhelming dry soils and creating significant flash flooding. Central Texas is currently home to some of the worst drought in the United States and bone-dry soils flood very quickly.

Camp Mystic is a nondenominational Christian summer camp for girls in western Kerr County. The camp is located at a dangerous confluence of the South Fork Guadalupe River and Cypress Creek, where flood waters converged.

Camp Mystic has two sites, both of which overlap with either the floodway or areas the federal government has determined have a 1% or 0.2% annual chance of flooding.

Officials have not shared how many of the Camp Mystic girls perished in the floods. At least 10 girls and one counselor remain missing as of Sunday evening.

Ten minutes north on the South Fork is Camp La Junta, a boys camp. Some of Camp La Junta’s property also coincides with areas known to flood, though several of its buildings are located in the lower-risk zone, or outside the flood zones entirely.

Wyndham Etheridge, a 14-year-old at Camp La Junta in Hunt, Texas, told CNN’s Fredricka Whitfield he woke up to people from all over the camp coming to “seek refuge” at his cabin. They stayed there, fearing the strong floodwaters could sweep them away.

As the water rose, they climbed into the loft of their cabin to escape, but it wasn’t safe, Etheridge said. “So at some point we just decided … we could go to bed for a little bit, but then we woke up again to more water,” he said.

Etheridge’s parents were among the lucky who received word that their child was safe and could be picked up. “All those boys were pretty traumatized,” said Amy Etheridge, Wyndham’s mother.

Everyone at Camp La Junta has been safe and accounted for, the camp announced Friday.





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‘Love Island’s Cierra Ortega’s Parents Call For “Compassion” Amid Backlash & Villa Exit

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Cierra Ortega’s parents have seen the messages directed at the Love Island USA Islander and are calling for “compassion” amid the backlash and her exit from the villa.

Following Season 7, Episode 30 streaming on Peacock, Cierra’s parents released a statement on social media after it was confirmed she would no longer be part of the dating series.

“As Cierra’s parents, this has been one of the most painful weeks of our lives,” the parents said in a statement posted on Instagram. “We’ve seen the posts, the headlines, the hurt and the hate. And while Cierra hasn’t seen any of it yet, we have. And so have the people who love her.”

The statement continued, “We’re not here to justify or ignore what’s surfaced. We understand why people are upset, and we know accountability matters. But what’s happening online right now has gone far beyond that. The threats. The cruel messages. The attacks on her family, her friends, even her supporters, it’s heartbreaking. It’s uncalled for. And no one deserves that kind of hate, no matter what mistake they’ve made.”

An old social media post Cierra made resurfaced, where she references her eyes, and uses a racial slur that has been used to denigrate the Asian community. Since the post went viral, Cierra began losing thousands of followers. Before the backlash, Cierra was close to hitting 1M on Instagram, but when Love Island USA fans learned of her using the racial slur, her follower count began to drop, which stands at 683k now.

RELATED: All Of Ariana Madix’s Outfits As Host Of ‘Love Island USA’ Season 7

Cierra’s parents noted that she had not seen anything, as she was still sequestered pending the episode’s release.

“We know our daughter. We know her heart. And when she returns, we believe she’ll face this with honesty, growth, and grace,” the parents added. “While she’ll always be our little girl, she’s also a woman, one who will take responsibility in her own time and her own voice.”

RELATED: ‘Love Island: Beyond The Villa’ Trailer & Premiere Date Set At Peacock

Cierra’s parents ended the statement saying, “Until then, we’re simply asking for compassion. For patience. For basic human decency. Not just for her, but for everyone caught in the middle of this.
Thank you to those who’ve continued to show love, even when it’s not easy.”

Cierra Ortega’s parents release statement

Instagram / cierra.ortega



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Cautious optimism for Gaza ceasefire breakthrough as Netanyahu visits US

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Yolande Knell

Middle East correspondent

Reuters US President Donald Trump welcomes Israeli Prime Minister Benjamin Netanyahu to the White House in Washington, D.C., U.S., April 7, 2025Reuters

US President Donald Trump welcomes Israeli Prime Minister Benjamin Netanyahu to the White House in April

After 21 months of war, there are growing hopes of a new Gaza ceasefire announcement as Israel’s Prime Minister Benjamin Netanyahu meets US President Donald Trump in Washington.

Trump previously told reporters he had been “very firm” with Netanyahu about ending the conflict and that he thought “we’ll have a deal” this week.

“We are working to achieve the deal that has been discussed, under the conditions we have agreed,” the veteran Israeli PM said before boarding his plane. “I believe that the conversation with President Trump can definitely help advance this outcome, which we all hope for.”

Indirect talks between Israel and Hamas on a US-sponsored proposal for a 60-day ceasefire and hostage release deal resumed in Qatar on Sunday evening.

However, it is unclear whether key differences that have consistently held up an agreement can be overcome.

Only cautious optimism is being expressed by weary Palestinians living in dire conditions amid continuing daily Israeli bombardment, and the distressed families of Israeli hostages still held by Hamas.

“I don’t wish for a truce but a complete stop to all war. Frankly, I’m afraid that after 60 days the war would restart again,” says Nabil Abu Dayah, who fled from Beit Lahia in northern Gaza to Gaza City with his children and grandchildren.

“We got so tired of displacement, we got tired of thirst and hunger, from living in tents. When it comes to life’s necessities, we have zero.”

On Saturday evening, large rallies took place urging Israel’s government to seal a deal to return some 50 hostages from Gaza, up to 20 of whom are believed to be alive.

Some relatives questioned why the framework deal would not free all captives immediately.

“How does one survive under such conditions? I’m waiting for Evyatar to return and tell me himself,” said Ilay David, whose younger brother, a musician, was filmed by Hamas in torment as he watched fellow hostages being released earlier this year during the last, two-month-long ceasefire.

“This is the time to save lives. This is the time to rescue the bodies from the threat of disappearance,” Ilay told a crowd in Jerusalem.

“In the rapidly changing reality of the Middle East, this is the moment to sign a comprehensive agreement that will lead to the release of all the hostages, every single one, without exception.”

AFP Families of Israeli hostages held by Hamas in Gaza protest outside the Israeli military's headquarters in Tel Aviv, Israel (5 July 2025)AFP

The Israeli hostages’ families are urging the US president to broker a deal that secures the release of all of those held in Gaza

Netanyahu is visiting the White House for the third time since Trump returned to power nearly six months ago.

But the leaders will be meeting for the first time since the US joined Israeli attacks on Iranian nuclear sites and then brokered a ceasefire between Israel and Iran.

There is a strong sense that the recent 12-day war has created more favourable circumstances to end the Gaza war.

After months of low popularity ratings, the Israeli PM has been bolstered by broad public support for the Iran offensive and analysts suggest he now has more leverage to agree to a peace deal over the strong objections of his far-right coalition partners, who want Israel to remain in control of Gaza.

Hamas is seen to have been further weakened by the strikes on Iran – a key regional patron – meaning it could also be more amenable to making concessions needed to reach an agreement.

Meanwhile, Trump is keen to move on to other priorities in the Middle East.

These include brokering border talks between Israel and Syria, returning to efforts to normalise relations between Israel and Saudi Arabia, and completing unfinished business with Iran, involving possible negotiations on a new nuclear deal.

For months, ceasefire talks between Israel and Hamas have been deadlocked over one fundamental difference.

Israel has been ready to commit to a temporary truce to return hostages but not an end to the war. Hamas has demanded a permanent cessation of hostilities in Gaza and a full pullout of Israeli troops.

The latest proposal put to Hamas is said to include guarantees of Washington’s commitment to the deal and to continued talks to reach a lasting ceasefire and the release of all the hostages.

Nothing has been officially announced, but according to media reports the framework would see Hamas hand over 28 hostages – 10 alive and 18 dead – in five stages over 60 days without the troubling handover ceremonies it staged in the last ceasefire.

There would be a large surge in humanitarian aid entering Gaza.

After the return of the first eight living hostages on the first day of the agreement, Israeli forces would withdraw from parts of the north. After one week, the army would leave parts of the south.

On Day 10, Hamas would outline which hostages remain alive and their condition, while Israel would give details about more than 2,000 Gazans arrested during the war who remain in “administrative detention” – a practice which allows the Israeli authorities to hold them without charge or trial.

As seen before, large numbers of Palestinians would be released from Israeli jails in exchange for hostages.

Reuters Israeli soldiers operate in Gaza, as seen from the Israeli side of the border (6 July 2025)Reuters

The Israeli military’s chief of staff said last week that it was nearing the completion of its war goals

President Trump has described this as the “final” truce proposal and said last week that Israel had accepted “the necessary conditions” to finalise it.

On Friday, Hamas said it had responded in a “positive spirit” but expressed some reservations.

A Palestinian official said sticking points remained over humanitarian aid – with Hamas demanding an immediate end to operations by the controversial Israeli and American-backed Gaza Humanitarian Foundation (GHF) and a return to the UN and its partners overseeing all relief efforts.

Hamas is also said to be questioning the timetable for Israeli troop withdrawals and operations of the Rafah crossing between southern Gaza and Egypt.

Netanyahu’s office stated on Saturday that the changes wanted by Hamas were “not acceptable” to Israel.

The prime minister has repeatedly said that Hamas must be disarmed, a demand the Islamist group has so far refused to discuss.

EPA Displaced Palestinians gather outside a charity kitchen for food, in Khan Younis, southern Gaza (30 May 2025)EPA

The humanitarian situation in Gaza is continuing to deteriorate

In Israel, there is growing opposition to the war in Gaza, with more than 20 soldiers killed in the past month, according to the military.

The Israeli military’s chief of staff, Lt Gen Eyal Zamir, said last week that it was nearing the completion of its war goals and signalled that the government must decide whether to move ahead with a deal to bring home hostages or prepare for Israeli forces to re-establish military rule in Gaza.

Polls indicate that two-thirds of Israelis support a ceasefire deal to bring home the hostages.

In Gaza, some residents express fears that the current wave of positivity is being manufactured to ease tensions during Netanyahu’s US trip – rationalising that this happened in May as Trump prepared to visit Arab Gulf states.

The coming days will be critical politically and in humanitarian terms.

The situation in Gaza has continued to deteriorate, with medical staff reporting acute malnutrition among children.

The UN says that with no fuel having entered in over four months, stockpiles are now virtually gone, threatening vital medical care, water supplies and telecommunications.

Israel launched its war in Gaza in retaliation for the Hamas-led attacks on 7 October 2023, which killed about 1,200 people and led to 251 others being taken hostage.

Israeli attacks have since killed more than 57,000 people in Gaza, according to the Hamas-run health ministry. The ministry’s figures are quoted by the UN and others as the most reliable source of statistics available on casualties.



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