Business
Tempus Announces the Acquisition of Paige

Paige’s strong foundation in pathology and AI is rooted in its proprietary dataset of almost 7 million digitized pathology slides that are clinically annotated
CHICAGO, August 22, 2025–(BUSINESS WIRE)–Tempus AI, Inc. (NASDAQ: TEM), a technology company leading the adoption of AI to advance precision medicine, today announced the acquisition of Paige, an AI company specializing in digital pathology. The acquisition allows Tempus to grow its dataset, expand its experienced technical team, and establish a strong footprint in digital pathology with an industry leading technology portfolio.
Founded in 2017, Paige has developed and deployed several AI applications, including the first FDA-cleared AI application in pathology, allowing researchers and pathologists to better detect cancer, which enables care teams to make more precise and informed treatment decisions. Paige has developed and refined its products through a dataset that includes almost 7 million digitized pathology slide images and associated clinical and molecular data, stripped of patient identifiers to protect privacy. Leveraging a dataset of de-identified data and images that spans 45 countries and diverse genders, races, ethnicities, and regions, Paige has also developed the first million-slide foundation model for cancer, empowering researchers and life sciences companies to better understand pathology data, and enabling the advancement of drug discovery and development.
“As we embark upon building the largest foundation model that’s ever been built in oncology, the acquisition of Paige substantially accelerates our efforts,” said Eric Lefkofsky, Founder and CEO of Tempus. “Paige is a leader in digital pathology and has amassed one of the most comprehensive digital pathology datasets in the world through its relationship with Memorial Sloan Kettering Cancer Center. We believe both the Paige team, with their deep generative AI experience, and the dataset they have built, will be catalytic across all of our AI efforts.”
“We’ve always believed that the future of cancer care and precision medicine lies in harnessing the full potential of AI to redefine what’s possible in digital pathology and transform how cancer is detected, understood, and treated,” said Razik Yousfi, CEO and CTO of Paige. “By joining forces with Tempus, a company already making remarkable strides in oncology diagnostics, we can bring our innovations to a broader patient population and deliver even greater impact. We are confident this partnership is uniquely positioned to maximize and expand the reach of our technology, ensuring it fulfills our mission of delivering powerful, data-driven insights.”
Business
Postal traffic into US plunges by more than 80% after Trump ends exemption | US news

Postal traffic into the United States plunged by more than 80% after the Trump administration ended a tariff exemption for low-cost imports, the United Nations postal agency said Saturday.
The Universal Postal Union says it has started rolling out new measures that can help postal operators around the world calculate and collect duties, or taxes, after the US eliminated the so-called “de minimis exemption” for lower-value parcels.
Eighty-eight postal operators have told the UPU that they have suspended some or all postal service to the United States until a solution is implemented with regard to US-bound parcels valued at $800 or less, which had been the cutoff for imported goods to escape customs charges.
“The global network saw postal traffic to the US come to a near-halt after the implementation of the new rules on Aug 29, 2025, which for the first time placed the burden of customs duty collection and remittance on transportation carriers or US Customs and Border Protection agency-approved qualified parties,” the UPU said in a statement.
The UPU said information exchanged among postal operators through its electronic network showed traffic from its 192 member countries – nearly all the world countries – had fallen 81% on 29 August, compared with a week earlier.
The agency, based in Bern, Switzerland, said the “major operational disruptions” have occurred because airlines and other carriers indicated they weren’t willing or able to collect such duties, and foreign postal operators had not established a link to CBP-qualified companies.
Before the measure took effect, the postal union sent a letter to the US secretary of state Marco Rubio to express concerns about its impact.
The de minimis exemption has existed in some form since 1938, and the administration says it has become a loophole that foreign businesses exploit to evade tariffs and that criminals use to get drugs into the US.
Purchases that previously entered the US without needing to clear customs now require vetting and are subject to their origin country’s applicable tariff rate, which can range from 10% to 50%.
While the change applies to the products of every country, US residents will not have to pay duties on incoming gifts valued at up to $100, or on up to $200 worth of personal souvenirs from trips abroad, according to the White House.
The UPU said its members had not been given enough time or guidance to comply with the procedures outlined in the executive order Donald Trump signed on 30 July to eliminate the duty-free eligibility of low-value goods.
Business
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Business
Reshuffle of junior ministers raises fears over future of Labour’s workers’ rights bill | Labour

Keir Starmer has sought to tighten his grip on his government with a wave of junior ministerial changes that has sidelined allies of the unions, raising questions over the future of Labour’s workers’ rights package.
The reshuffle has been used by Downing Street to signal a tougher stance on immigration in an apparent bid to take on Reform UK, with Shabana Mahmood – a self-described social conservative rising star – now in charge of the Home Office, supported by Sarah Jones who returns to her former policing brief.
Justin Madders, the employment rights minister, was one of the first on the junior benches to be sacked on Saturday. Despite being seen as one of the architects of Labour’s “new deal for working people”, Madders’ departure was not formally announced in No 10’s list of appointments. Instead, he revealed the news himself.
“It has been a real privilege to serve as minister for employment rights and begin delivering on our plan to make work pay,” he said on X. “Sadly it is now time to pass the baton on – I wish my successor well & will do what I can to help them make sure the ERB is implemented as intended.”
Madders’ removal, along with Rayner’s forced departure from her two government positions and post as Labour’s deputy leader, removes the key figures who helped design Labour’s employment rights bill – a policy unions praised as the government’s most ambitious commitment to workers’ rights in decades.
Starmer will also not attend this year’s TUC conference, a decision that has intensified concerns and rumours among unions and some inside Labour that the government is distancing itself. Rayner was the cabinet minister closest to the unions, and Madders had been given the job of turning the new deal into legislation.
Peter Kyle, a close ally of Starmer, was promoted to lead the business department on Friday, meaning he will oversee the employment rights brief.
Allies of Rayner who remain in government believe a fight is looming over workers’ rights. With Rayner and Madders gone, they believe Kyle has the ability to water down the bill – a package they feel many from the centre of the party were never comfortable with. The issue is likely to become factional, given polls show stronger employment protections remain popular with voters flirting with Reform UK.
The package had promised sweeping reforms including day one rights for workers, a ban on zero-hours contracts and stronger protects against fire-and-rehire. A union chief told the Guardian: “Rayner was the closest minister to the unions and her team have played an important role in pushing key parts of the employment rights bill through government.
“The commitment to the bill is there from Keir so I’m less worried about that, but more worried about the broader sense of who actually understands the unions, and has the personal relationships.”
Ellie Reeves has been shifted from her role as party chair to solicitor general and will no longer attend cabinet. She has been replaced by Anna Turley. Georgia Gould, from Labour’s 2024 intake, has been promoted to education minister.
For Starmer, the cabinet reshuffle was about showing decisive leadership in the midst of a major crisis, to which as his chief secretary, Darren Jones, alluded. But this junior reshuffle for many shows a broader ideological return that sees the government more cemented under centrist control, and potential fights with the unions along the way.
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Meanwhile, the shake-up at the Home Office will be taken as a sign of strength by many within government. Mahmood, the new secretary of state, will lead a refreshed team that now includes Sarah Jones, a former shadow minister who has long wanted to return to the brief. Jones has been described by some as serious about public safety and police reform, and is well regarded in industry after her work on steel and the industrial strategy within the business department.
Dame Diana Johnson has been replaced by Jones and will now serve as a minister in the Department for Work and Pensions, while Dan Jarvis will remain a minister in the Home Office and has also been made a Cabinet Office minister.
Jason Stockwood, the former chair of Grimsby Town football club, will take a seat in the House of Lords to become investment minister as part of Starmer’s ministerial shake-up. He was Labour’s candidate for Greater Lincolnshire mayor but was beaten by Reform’s Andrea Jenkyns.
The local government minister Jim McMahon has been sacked and will return to the backbenches, along with Maria Eagle, the defence minister. Catherine McKinnell resigned as minister of state for school standards, which included overseeing Send reform. She said she declined the opportunity to stay in government.
Darren Jones dismissed the idea that Rayner’s departure could expose divisions within the Labour party, after Nigel Farage said “splits” will open.
“Nigel Farage is wrong there,” Jones told Sky News. “The Labour party is not going to split and there won’t be an early election.”
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