AI Research
Prediction: 2 Artificial Intelligence (AI) Stocks Will Be Worth More Than Palantir Technologies by 2030

Shopify and Uber Technologies could match Palantir’s current market value within five years.
Palantir Technologies shares have advanced 1,760% since the launch of its artificial intelligence platform in April 2023. Its market capitalization now stands at $369 billion as of September 8, which puts it among the 30 largest public companies in the world.
I think Shopify (SHOP -1.86%) and Uber Technologies (UBER 1.05%) can surpass Palantir’s current market capitalization within five years. Here’s what that means for shareholders:
- Shopify is worth $189 billion. Its market value must increase 96% to hit $370 billion, in which case the stock would return more than 14% annually over the next five years.
- Uber is worth $197 billion. Its market value must increase 88% to hit $370 billion, in which case the stock would return more than 13% annually over the next five years.
Importantly, the S&P 500 (^GSPC 0.27%) has historically advanced roughly 10% per year, so my predictions almost certainly imply market-beating returns for Shopify and Uber shareholders. Here’s why I’m confident.
Image source: Getty Images.
1. Shopify
Shopify reported excellent financial results in the second quarter, beating estimates on the top and bottom lines. Revenue increased 31% to $2.6 billion as growth accelerated across North American, Europe, and Asia-Pacific. Non-GAAP net income increased 35% to $0.35 per diluted share.
The investment thesis for Shopify centers on its leadership in e-commerce software. Its platform helps merchants manage their businesses across physical and digital storefronts from a single dashboard. The company also provides adjacent solutions for payments, advertising, logistics, and cross-border commerce.
Shopify is focused on several strategic growth areas, including business-to-business (B2B) commerce, a category that is three times bigger than business-to-consumer (B2C) commerce and growing just as quickly. Forrester Research last year recognized Shopify as a leader in B2B commerce solutions, validating its push into the market. The company said B2B sales increased 101% in the second quarter.
Shopify is leaning into demand for artificial intelligence (AI). Shopify Magic is a suite of AI features that help merchants automate tasks like writing product descriptions, generating marketing content, and providing customer support. Additionally, the company earlier this year introduced an AI tool that builds entire online storefronts from a few keywords.
Wall Street expects Shopify’s earnings to increase at 34% annually during the next three to five years. That makes the current valuation of 81 times earnings look somewhat expensive. But if Shopify meets the consensus estimate, its price-to-earnings multiple could fall to 38 while its market value increased 100% to $378 billion by mid-2030. That means Shopify can surpass Palantir’s current market value within five years.
2. Uber Technologies
Uber reported encouraging financial results in the second quarter. beating the consensus estimate on the top line and matching the consensus estimate on the bottom line. Revenue increased 18% to $12.7 billion, an acceleration from 14% growth in the previous quarter, because of strength in the mobility and delivery segments. GAAP net income increased 34% to $0.63 per diluted share.
Uber may not be top of mind when investors think about artificial intelligence stocks, but the company uses AI to set prices, match drivers and riders, and optimize routes. Moreover, its position as the largest on-demand mobility and delivery platform in the world makes it an ideal partner for autonomous driving companies that want to commercialize robotaxi services.
Uber has partnered with 20 autonomous driving companies, including Alphabet‘s Waymo, Pony AI, and WeRide. Robotaxis are already available on its platform in four markets: Atlanta, Austin, and Phoenix in the United States; and Abu Dhabi in the United Arab Emirates. Uber expects about five more deployments in 2025, with more to follow in 2026.
Additionally, Uber in some cases is helping partner companies develop autonomous driving technology. “An underappreciated aspect of our strategy is just how central we are to the real-world AI revolution,” said CEO Dara Khosrowshahi in prepared remarks. “The advanced AI systems that perceive, predict, and make split-second decisions on the road need enormous amounts of data, and Uber has the most relevant mobility ride-hail dataset in the world.”
Wall Street expects Uber’s earnings to increase at 22% annually over the next three to five years. That makes the current valuation of 16 times earnings look relatively cheap. And if Uber meets that consensus, its price-to-earnings ratio could fall to 12 while its market value increased 105% to $387 billion by mid-2030. That means Uber can surpass Palantir’s current market value within five years.
Trevor Jennewine has positions in Palantir Technologies and Shopify. The Motley Fool has positions in and recommends Alphabet, Palantir Technologies, Shopify, and Uber Technologies. The Motley Fool has a disclosure policy.
AI Research
AI, Robotics Could Sort Trash in South Hampton Roads, Va.

(TNS) — Representatives of the region’s waste disposal authority are making the rounds at city meetings this month to lay the groundwork for long-term contract extensions they say will extend use of the regional landfill through the end of the century.
Southeastern Public Service Authority (SPSA) is asking South Hampton Roads cities and counties to renew their trash contracts for 25 years instead of an upcoming 10-year extension.
The longer-term contracts are needed to ensure that SPSA’s third-party provider will invest $200 million in new facilities to sort recyclables from solid waste across the region, SPSA Board of Directors Chairman Tom Leahy told the Virginia Beach City Council Tuesday.
The new sorting process will eventually eliminate the need for blue curbside recycling cans and for residents to sort recyclables from solid waste.
“All the waste would go into a single can, collected by a single truck at the curbside,” said Leahy. “Recycling and reuse would occur after collection.”
SPSA handles hundreds of thousands of tons of waste for Chesapeake, Norfolk, Portsmouth, Suffolk and Virginia Beach, in addition to surrounding localities including Franklin and Southampton and Isle of Wight counties.
SPSA has been in need of alternative waste disposal services since the 2024 closure of the WIN Waste plant, formerly known as the Wheelabrator facility, which burned 80% of the region’s trash for decades. The former plant also converted waste into steam energy for the Norfolk Naval Shipyard. Then, 30% of the ash left over was diverted to the landfill.
The plant’s closure put pressure on the regional landfill, which will reach capacity in a few decades.
SPSA is in the process of finalizing negotiations with Commonwealth Sortation LLC, a subsidiary of AMP Robotics — a Colorado-based alternative waste disposal provider that uses artificial intelligence and robotics to extract mixed recyclables and organic material from municipal solid waste.
The process will divert 50% of SPSA’s waste from the landfill and extend the landfill’s capacity through 2095, Leahy said.
Commonwealth Sortation plans to invest approximately $200 million in new processing facilities, but wants a guarantee that SPSA’s member communities are in for the long haul. The company is currently operating out of a facility in Portsmouth and plans to expand its operations.
An agreement between SPSA’s board and Commonwealth Sortation is expected by the end of this year, but it’s contingent on most of the localities agreeing to the 25-year extension, Leahy said.
The Virginia Beach City Council is scheduled to vote on the contract extension Oct. 7. Cities’ agreements with SPSA are scheduled to renew for an additional 10 years in 2027. The proposed amendment would extend each localities’ contract to June 30, 2052.
“Recycling’s pretty popular with our citizens, and this will make everybody with a black can be a recycler,” said Vice Mayor Rosemary Wilson. “It’s really good news environmentally for all of us.”
Tipping fee increases associated with the new process are not expected to be higher than what large cities like Virginia Beach that offer curbside recycling are already incurring.
“We won’t necessarily see a cost increase associated with this transaction,” said City Manager Patrick Duhaney.
Several cities recently incurred cost increases when they renewed recycling contracts with TFC Recycling, including Virginia Beach and Norfolk. Chesapeake did away with curbside recycling in 2022 as costs increased.
The average number of homes using curbside recycling in Virginia Beach was 125,000 in 2024. Virginia Beach residents currently pay for curbside recycling as part of their trash collection. The solid waste collection fee is $30.55 per month.
Virginia Beach’s contract with TFC Recycling will overlap with the new SPSA contract and general fund support may be needed to cover the cost, City Manager Patrick Duhaney said.
©2025 The Virginian-Pilot. Visit pilotonline.com. Distributed by Tribune Content Agency, LLC.
AI Research
Sandia National Laboratories’ Research Team Develop AI Algorithms to Detect Physical Issues, Cyberattacks within Grid

Researchers at Sandia National Laboratories have developed AI algorithms to detect physical problems, cyberattacks and both at the same time within the grid.
“As more disturbances occur, whether from extreme weather or from cyberattacks, the most important thing is that operators maintain the function and reliability of the grid,” said Shamina Hossain-McKenzie, a cybersecurity expert and leader of the project. “Our technology will allow the operators to detect any issues faster so that they can mitigate them faster with AI.”
Adrian Chavez, a cybersecurity expert involved in the project, added that as the neural network runs on single-board computers, or existing smart grid devices, it will be able to protect older equipment as well as the latest equipment lacking only cyber-physical coordination.
The package of code works at the local, enclave and global levels. At the local level, the code monitors for abnormalities at the specific device where it is installed, at the enclave level, devices in the same network share data and alerts to provide the operator with better information on whether the issue is localized or happening in multiple places and at the global level, only results and alerts are shared between systems owned by different operators.
Thus, operators will receive early alerts of cyberattacks or physical issues their neighbours are seeing and protect proprietary information. The Sandia team collaborated with experts at Texas A&M University to create secure communication methods, between grids owned by different companies, Hossain-McKenzie added.
According to Logan Blakely, a computer science expert who led development of the AI components, the challenge in detecting cyber-physical attacks is combining the constant stream of physical data with intermittent packets of cyber data.
Physical data such as the frequency, voltage and current of the grid is reported 60 times a second, while cyber data such as other traffic on the network is more irregular, Blakely said. The team used data fusion to extract the important signals in the two different kinds of data.
The team also used an autoencoder neural network, which classifies the combined data to determine if it fits with the pattern of normal behavior or there are abnormalities with the cyber data, physical data or both, Hossain-McKenzie said. For example, an increase in network traffic is predicted to indicate a denial-of-service attack while a false-data-injection attack can include atypical physical and cyber data, Chavez added.
Autoencoder neural networks do not need to be trained on data labelled with every type of issue coming up as compared to other kinds of AI, Blakely said. However, the network only requires huge amount of data from normal operations for training.
After the team constructed the autoencoder neural network, they put it to the test in three different ways. First, they tested the autoencoder in an emulation environment, which includes computer models of the communication-and-control system used to monitor the grid and a physics-based model of the grid itself, Hossain-McKenzie said.
The team used the environment to model a variety of cyberattacks or physical disruptions, and to provide normal operational data for the AI to train on. The collaborators from Texas A&M University assisted with the emulation testing.
Secondly, the team incorporated the autoencoder onto single-board computer prototypes that were tested in a hardware-in-the-loop environment, Hossain-McKenzie said. In hardware-in-the-loop testing, researchers connected a real piece of hardware to software simulating various attack scenarios or disruptions.
When the autoencoder is on a single-board computer, it can read the data and implement the algorithms faster than a virtual implementation of the autoencoder can in an emulation environment, Chavez said. Hardware implementations are a hundred or thousand times faster than software implementations, he added.
The team is working with Sierra Nevada Corporation to test Sandia’s autoencoder AI on the company’s existing cybersecurity device called Binary Armor, Hossain-McKenzie said.
The team is testing both formats, single-board prototypes interfaced with the grid and the AI package on existing devices, in the real world at the Public Service Company of New Mexico’s Prosperity solar farm as part of a Cooperative Research and Development Agreement, Hossain-McKenzie said. The tests started in summer 2024, Chavez said.
The project expanded upon a previous R&D 100 Award-winning project called the Proactive Intrusion Detection and Mitigation System, which focused on detecting and responding to cyber intrusions in smart inverters on solar-panels, Hossain-McKenzie said. The team is expanding upon the autoencoder AI in similar projects, she added.
The team filed a patent on the autoencoder AI and is looking for corporate partners to deploy and hone the technology in the real world, Hossain-McKenzie said. The autoencoder is expected to be used to protect other critical infrastructure systems such as water and natural gas distribution systems, factories, even data centers, Chavez said.
The project is funded by Sandia’s Laboratory Directed Research and Development program.
AI Research
PharmaNest, NIH and VCU Launch Confirmatory Retrospective Outcome Study With 1,765 Patients to Advance AI-Driven Digital Pathology in MASLD

PharmaNest Inc. announced today a multi-institutional research collaboration with Virginia Commonwealth University (VCU) and the National Institutes of Health (NIH) to confirm the prognostic performance of artificial intelligence (AI) powered digital pathology biomarkers in metabolic dysfunction-associated steatotic liver disease (MASLD) in a retrospective cohort of 1,765 patients with MASH (NASH CRN DB2 Cohort)
PRINCETON, N.J., September 11, 2025 (Newswire.com)
–
PharmaNest Inc. announced today a multi-institutional research collaboration with Virginia Commonwealth University (VCU) and the National Institutes of Health (NIH) to confirm the prognostic performance of artificial intelligence (AI) powered digital pathology biomarkers in metabolic dysfunction-associated steatotic liver disease (MASLD) in a retrospective cohort of 1,765 patients with MASH (NASH CRN DB2 Cohort).
The collaboration unites Professor Arun Sanyal, M.D. (Director, Stravitz-Sanyal Institute for Liver Disease and Metabolic Health at VCU), Dr. David Kleiner, M.D., Ph.D. (Principal Investigator, NIH NASH CRN), and Dr. Mathieu Petitjean, Ph.D. (CEO, PharmaNest). Together they will lead the Digital Pathology and AI for Liver Outcomes Study – 2 (DPAILO-2, NCT06493253), an NIH NASH CRN supported ancillary study.
Study Highlights:
Primary Objective: Evaluate the prognostic value of PharmaNest’s FibroNest Ph-FCS biomarker, a high-resolution single-fiber AI-driven fibrosis continuous score, in predicting hepatic decompensation.
Comparative Goals: Compare Ph-FCS against conventional fibrosis staging and some non-invasive tests.
Exploratory Aims: Use single-fiber clustering (FibroMAP) on paired biopsies to uncover novel fibrosis risk phenotypes.
The study uses 1,765 anonymized digital pathology liver biopsies from the NAFLD Adult Database 2, stained with Masson’s Trichrome and scanned at ultra-high resolution. PharmaNest will process the images and generate biomarkers on an accelerated basis to ensure timely results, which will be integrated into a secure VCU-hosted database for statistical analysis.
VCU will oversee governance, NIH compliance, and statistical analyses.
PharmaNest will sponsor, analyze images, and deliver AI-derived biomarkers within the 2025 timeline.
NIH’s NASH CRN will provide clinical oversight and ensure alignment with network standards.
“This collaboration represents an important step toward establishing robust histological biomarkers that can guide patient management and accelerate drug development in MASLD,” said Professor Arun Sanyal, M.D. Principal investigator.
“By combining the depth of NASH CRN’s clinical expertise with PharmaNest’s AI-powered single-fiber pathology and continuous fibrosis scores, we aim to accurately and quantitatively assess fibrosis progress and treatment response, and so provide better information for hepatologists and their patients,” said Dr. David Kleiner, M.D., Ph.D., NIH’s NASH CRN Liaison.
“PharmaNest is proud to bring its FibroNest™ Digital Pathology platform to this partnership. This landmark study will validate the strong prognostic power of our continuous biomarker Ph-FCS-already proven in over 400 patients with more than 10 years of follow-up-paving the way for regulatory-grade digital biomarkers in liver disease and unlocking new discoveries with our FibroMAP™ spatial histology tools.” said Dr. Mathieu Petitjean, Ph.D. CEO at PharmaNest.
About the Partners
The Stravitz-Sanyal Institute for Liver Disease and Metabolic Health at Virginia Commonwealth University (VCU) is dedicated to advancing research, clinical care, and education to improve the prevention, diagnosis, and treatment of liver and metabolic diseases, fostering innovation and collaboration to reduce the global burden of these conditions.
NASH Clinical Research Network (NASH CRN) is an NIH-funded collaborative network advancing research in nonalcoholic fatty liver disease and steatohepatitis.
PharmaNest Inc. is a digital pathology company pioneering AI-driven single-fiber analysis for fibrosis and inflammation in preclinical and clinical studies.
Contact Information
Mathieu Petitjean
CEO
info@pharmanest.com
(609) 375 2003
Source: PHARMANEST
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