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Opening the black box of machine learning-controlled plasma treatments

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Understanding machine learning modifies cold atmospheric plasma medicine delivery in cancer treatments without being trained on detailed plasma parameters.

Although artificial intelligence (AI) can adapt to changing conditions and achieve desired outcomes, how algorithms “understand” and adjust to inputs can be a mystery.

Lin et al. sought to uncover this “black box” in AI-controlled cold atmospheric plasma (CAP) treatments, an approach that induces apoptosis in diseased cells while preserving healthy ones. In previous work, they developed a machine learning (ML) system that predicts the post-treatment state of cancer cell targets and adjusts treatment accordingly. However, they didn’t know how the ML system achieved this outcome without an understanding of specific plasma parameters.

Using an AI-based optical emission spectroscopy (OES) spectra translation algorithm, the authors reverse engineered real-time chemical accumulations above cell medium surfaces. They found that, despite changing conditions, the ML algorithm alters experimental parameters to achieve the same therapeutic outcomes. The application of a Fourier transformation on OES spectra and chemical kinetics analysis revealed how the ML algorithm independently captured additional layers of physics information relying solely on cell viability status, without human input of this information, to achieve the precision and reliability of their AI-controlled CAP model.

“Beyond plasma medicine, similar approaches could advance machine learning-based control in fields like electric propulsion for satellites, plasma-based microfabrication, fusion reactor management, and many other plasma applications” said author Michael Keidar.

Next, the team looks to extend the scope of control that was demonstrated in this paper.

“Instead of limiting the AI to adjusting treatment duration, we plan to authorize and train the AI to control multiple plasma parameters simultaneously, including voltage, gas flow rate, and even additional external electric fields,” said author Li Lin. “In doing so, we aim to tailor therapy to the specific needs of each patient.”

Source: “Low-temperature plasma adaptation in the course of machine learning controls of plasma medicine,” by Li Lin, Qihui Wang, Zichao Hou, Michael Keidar, Physics of Plasmas (2025). The article can be accessed at https://doi.org/10.1063/5.0274614 .





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Google DeepMind CEO says AI bots haven’t hit “PhD-level” yet

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Artificial General Intelligence (AGI) appears to be the ultimate goal for most AI labs, including Google, Anthropic, and OpenAI, as they invest billions into the rapidly evolving landscape of cloud computing, GPUs, and other critical infrastructure.

Over the past few months, multiple reports have emerged suggesting that some of these companies are on the verge of achieving the coveted benchmark. However, the term has seemingly turned into a buzzword thrown around by executives in the space with a different meaning every time it’s mentioned in a conversation.



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Wake County school board to tackle several topics Tuesday, includes AI use in school, religious exemptions

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CARY, N.C. (WTVD) — Wake County school board is set to address several topics during its Tuesday meeting.

Board members will discuss how artificial intelligence is transforming education, how it is being used in schools, and the development of key policies surrounding AI in the largest district in the state.

Another major focus of the meeting is the development of a policy allowing parents to exercise religious exemptions.

This follows state lawmakers overturning Governor Roy Cooper’s veto of a bill granting parents the right to withdraw their children from topics such as LGBTQ history and the theory of evolution.

Under the proposed guidelines, parents would need to submit written requests specifying how the instruction conflicts with their child’s religious beliefs. If approved, students would receive alternative assignments, and parents could appeal if their requests are denied. The board is set to vote on the policy during the meeting.

An update on current staffing levels is also expected. According to the latest vacancy report, Wake County has 148 vacant teaching positions, 22 fewer than this time last year. There are 66 special education vacancies and 116 instructional assistant vacancies.

The board plans to address recruitment strategies for special education hires and hard-to-fill positions.

The district is also working to fill a vacant seat following the resignation of former board chair Lindsay Mahaffey, who is stepping down to spend more time with her family.

In Cary, the meeting begins with a work session at 3 p.m., followed by the regular board meeting to address these issues.

Note: This story will be updated.

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AI used for taking notes at UVM Medical Center – WCAX

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AI used for taking notes at UVM Medical Center  WCAX



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