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Dutch grid crisis exposes Europe’s AI energy infrastructure gap

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Europe’s digital ambitions collide with energy infrastructure limitations as the Netherlands experiences unprecedented grid congestion that serves as a harbinger for the continent’s AI future. The crisis emerged prominently today, when the Financial Times published comprehensive reporting revealing that more than 11,900 businesses await electricity network connections across the Netherlands, forcing network operators to ration power supply.

The situation demonstrates Europe’s unpreparedness for AI energy demands, with data centers requiring electricity consumption equivalent to 100,000 households each. According to the International Energy Agency, Europe accounts for approximately 15% of global data center electricity consumption at 70 TWh in 2024, yet this figure is projected to grow by more than 45 TWh by 2030 – a 70% increase that coincides with accelerated AI adoption across industries.

Summary

Who: Netherlands government, Tennet (national grid operator), more than 11,900 businesses awaiting connections, European Union member states, International Energy Agency, technology companies including ASML and Thermo Fisher

What: Electricity grid crisis forcing power rationing as AI data centers and electrification outpace infrastructure capacity, requiring €200 billion investment through 2040

When: Crisis emerged prominently January 13, 2025, with reporting showing years-long connection delays and infrastructure shortages expected to persist until mid-2030s

Where: Netherlands serving as early indicator for broader European challenges, with similar issues emerging in Belgium, United Kingdom, Germany, and Ireland

Why: Rapid electrification following 2023 Groningen gasfield closure, accelerated corporate gas transitions after 2022 EU energy crisis, and growing AI data center demands requiring infrastructure investment that hadn’t kept pace with gas dependency

Dutch infrastructure struggles under electrification pressure. The Netherlands moved fastest among European nations to electrify critical economic sectors after ending production at its Groningen gasfield in 2023. More than 2.6 million Dutch homes now feature solar panels on rooftops, while companies accelerated their transition away from gas following the EU’s energy price crisis in 2022. The rapid shift exposed infrastructure vulnerabilities that had developed over decades of gas dependency.

“The country had been so used to relying on its gas resources that power grid upgrades had not kept pace,” Tennet, the national power grid operator, acknowledged. The resulting bottlenecks create some of the highest electricity costs in western Europe, with monthly prices roughly €30 per megawatt hour higher than France this year.

Investment requirements reveal the scale of the challenge. The Dutch government estimates €200 billion in investment for cables and new substations through 2040. Some funding will come from Tennet’s German power grid sale to private investors, valued at approximately €20 billion. However, the majority must be covered through asset amortization, with consumers bearing the cost through tariff increases averaging 4.3% to 4.7% annually until 2034.

The situation particularly affects technology hubs. The Brainport region around Eindhoven, home to 750,000 people and advanced technology companies led by ASML, has lost investment due to power supply rationing. Jeroen Dijsselbloem, mayor of Eindhoven, stated: “Everything is going electric and electricity infrastructure needs to grow massively everywhere.” No significant new grid capacity will be installed in the region until 2027, according to Tennet figures.

Infrastructure gaps extend beyond local concerns. Grid operators face a shortage of 28,000 technicians needed to install necessary infrastructure. The technical demands are substantial: Eindhoven requires more than 100 medium-size substations and 4,000 small substations to meet growing demand.

Companies adapt through private solutions. Thermo Fisher, a US medical business with operations in Eindhoven, has maintained growth plans while investing in on-site battery storage and solar installations to counter grid congestion. Steve Reyntjens, leader of Thermo Fisher’s Eindhoven site, explained: “We continue to work with local officials and authorities to find a long-term solution on power grid capacity.”

AI amplifies energy demands across Europe. Data center electricity consumption has grown 12% annually since 2017, more than four times faster than total electricity consumption growth. The International Energy Agency projects global data center consumption will more than double to 945 TWh by 2030, driven primarily by AI development. Europe’s share of this growth represents a significant infrastructure challenge for national grids designed for previous consumption patterns.

Connection queues reveal system strain. The Netherlands faces up to 10-year wait times for new data center connections, the longest among surveyed jurisdictions. Germany experiences up to 7-year delays, while the United Kingdom faces 5-7 year queues. Ireland has paused new data center connections in Dublin until 2030. These delays reflect broader European infrastructure limitations as AI demands accelerate.

Grid congestion costs multiply across markets. Between 2019 and 2022, congestion management costs tripled in Germany, the United States, and Great Britain. The Netherlands experienced a sixfold increase during the same period. Despite decreasing natural gas prices reducing some costs, congestion volumes continue increasing across European markets.

PPC Land previously covered how digital marketing infrastructure faces similar energy challenges, with ad tech companies transitioning to renewable energy sources. Since 2022, PubMatic operates 100% of its global data centers on renewable energy, representing what the company describes as a long and expensive journey requiring assessment of different opportunities.

Research demonstrates the magnitude of AI’s energy footprint. According to the International Energy Agency’s comprehensive Energy and AI report, a typical AI-focused data center consumes as much electricity as 100,000 households, while the largest facilities under construction today will consume 20 times that amount. The report, based on a new global model and comprehensive dataset of data center electricity demand, reveals that AI workloads drive the most significant component of accelerated server electricity consumption growth.

The European Energy Research Alliance analysis emphasizes the complexity of integrating AI into energy systems. Their research indicates that AI applications in electricity markets have been increasingly applied across forecasting, production optimization, price estimation in wholesale markets, and grid management. However, the implementation faces challenges including data quality issues, proprietary restrictions, and the non-transparent nature of AI models.

Accelerated servers, primarily driven by AI technology adoption, are projected to grow by 30% annually according to the IEA analysis, while conventional server electricity consumption growth remains at 9% per year. This disparity highlights how AI specifically drives energy demand beyond traditional computing needs. Accelerated servers account for almost half of the net increase in global data center electricity consumption through 2030.

The marketing implications extend beyond infrastructure. As programmatic advertising growth reaches 72% in 2025, the energy requirements for processing billions of daily ad auctions compound the pressure on European grids. Data centers supporting programmatic advertising require consistent power availability to maintain real-time bidding capabilities across global markets.

European energy research reveals fundamental challenges ahead. The European Energy Research Alliance analysis of artificial intelligence implementation in the energy sector highlights that current applications focus on electricity market optimization, demand forecasting, and grid management. However, their research identifies significant barriers including data quality limitations, high input dimensionality, complex system behavior, and the non-transparent black-box nature of AI models.

The research demonstrates that AI methods face restrictions from proprietary or restricted data access, which particularly affects European energy markets where data sharing remains limited. This creates a paradox where AI systems require vast amounts of data to function effectively, yet the energy sector’s need for AI grows precisely because of data complexity and system integration challenges.

Grid connection delays compound across European markets. The International Energy Agency data shows connection queues varying dramatically by jurisdiction: Netherlands faces up to 10 years, Germany and the United Kingdom experience 5-7 years, while Ireland has paused new data center connections in Dublin until 2030. These delays reflect infrastructure limitations rather than bureaucratic inefficiencies, as congested grids cannot approve even priority applications.

Data center concentration exacerbates regional problems. Unlike distributed electric vehicle adoption, AI-focused data centers concentrate in specific geographic clusters, creating intense local demand that overwhelms regional grid capacity. Nearly half of US data center capacity exists in five regional clusters, a pattern emerging across European markets as operators seek optimal combinations of connectivity, cooling, and power availability.

The energy research indicates that successful AI integration in energy systems requires addressing fundamental infrastructure limitations first. The European Energy Research Alliance study notes that despite AI’s potential to optimize energy consumption patterns and grid management, current implementation remains limited by the very infrastructure constraints that AI could theoretically help resolve.

Investment patterns reveal European competitive risks. According to the IEA analysis, global investment in data centers nearly doubled since 2022, reaching half a trillion dollars in 2024. The United States accounts for 45% of global data center electricity consumption, followed by China at 25% and Europe at 15%. This distribution suggests Europe already trails in the infrastructure race that will determine AI leadership.

European electricity market structure creates additional complexity. The European Energy Research Alliance research highlights that electricity markets across the EU operate under different regulatory frameworks, network codes, and market designs. This fragmentation complicates the development of continent-wide AI energy solutions and infrastructure planning coordination.

The research emphasizes that AI’s application in energy markets faces regulatory challenges beyond technical limitations. The Electricity Market Regulation, Renewable Energy Directive, Network Codes and Guidelines, Energy Efficiency Directive, and Energy Performance of Buildings Directive all influence AI deployment in electricity markets. These regulatory layers, while designed to ensure grid stability and consumer protection, can slow AI adoption compared to markets with more unified regulatory approaches.

Technical efficiency studies demonstrate AI’s double-edged energy impact. According to research cited in the IEA report, an efficiency comparison of NPU, CPU, and GPU when executing object detection models like YOLOv5 shows significant variation in energy consumption per computation. These efficiency differences become critical as AI workloads scale, potentially offering pathways to reduce energy intensity while maintaining performance.

The European research indicates that edge intelligence and physics-informed machine learning represent emerging paradigms that could address some energy efficiency concerns. Edge computing can reduce data transmission energy requirements by processing information closer to sources, while physics-informed models potentially require less computational power by incorporating domain knowledge rather than relying solely on data-driven learning.

However, current implementation remains limited. The European Energy Research Alliance analysis notes that despite experimental success in controlled environments, widespread deployment of energy-efficient AI remains constrained by infrastructure limitations, skill gaps among decision-makers, and the complexity of integrating new technologies into existing energy systems.

Research reveals systemic European disadvantages. The combination of fragmented electricity markets, aging grid infrastructure, complex regulatory environments, and conservative investment approaches creates structural challenges for European AI energy development. Unlike markets with more centralized planning or newer infrastructure, European nations must navigate decades of accumulated infrastructure debt while simultaneously investing in AI-ready energy systems.

The analysis suggests that without coordinated European response, individual nations will face the Netherlands’ experience on a broader scale. Current national approaches to grid modernization lack the coordination necessary to support continent-wide AI development, potentially fragmenting European AI capabilities and undermining digital sovereignty objectives.

Energy system modeling research indicates that AI integration requires fundamental infrastructure redesign rather than incremental upgrades. The European Energy Research Alliance study emphasizes that traditional optimization methodologies, which have guided energy infrastructure development for decades, may prove insufficient for the real-time, high-computation demands of AI-integrated energy systems.

Studies show that successful energy system AI implementation requires addressing both the supply and demand sides simultaneously. While data centers represent highly concentrated demand points, AI applications for grid optimization, renewable energy integration, and demand response management require distributed intelligence capabilities that current European infrastructure cannot adequately support.

The research concludes that European energy systems face a transformation challenge comparable to the original electrification of the continent. Just as the transition from gas lighting to electric power required complete infrastructure replacement rather than modification, the AI energy transition demands new approaches to generation, transmission, distribution, and consumption management.

European officials warn of broader implications. Eefje van Gorp, Tennet spokesperson, emphasized that other countries should beware: “Belgium is in trouble. The UK is in trouble. In Germany there’s lots of trouble because in Germany all the wind is in the north and the demand is in the south.” These geographic mismatches between renewable energy generation and demand centers create additional transmission challenges.

Market analysis reveals accelerating AI adoption despite energy constraints. According to Gartner’s November 2024 prediction, power shortages will restrict 40% of AI data centers by 2027, creating a fundamental supply-demand imbalance that could reshape the global AI landscape. The research firm’s analysis indicates that energy availability, rather than computational capability or algorithmic advancement, may become the primary limiting factor for AI development.

The Deloitte study “Powering artificial intelligence – A study of AI’s environmental footprint – today and tomorrow” provides additional context for European challenges. Their research demonstrates that AI’s environmental impact extends beyond direct electricity consumption to include manufacturing of specialized hardware, cooling systems, and supporting infrastructure. This comprehensive footprint multiplies the infrastructure investment requirements facing European nations.

Goldman Sachs research on “Generational growth, AI/data center’s global power surge and the Sustainability impact” quantifies the investment challenge. Their analysis suggests that the scale of infrastructure investment required for AI-ready energy systems represents one of the largest capital deployment challenges in modern economic history, comparable to post-war reconstruction efforts or the original electrification of industrial economies.

Research institutions document the skills shortage component. The Grid Strategies 2023 Transmission Congestion Report, referenced in the International Energy Agency analysis, demonstrates that congestion management has become increasingly complex across multiple markets. The Netherlands’ shortage of 28,000 technicians reflects a broader European challenge where energy transition demands exceed available technical expertise.

The Electric Power Research Institute’s 2024 survey on “Utility Experiences and Trends Regarding Data Centers” reveals utility operators’ growing concern about data center load growth outpacing infrastructure development. Their research indicates that utilities face unprecedented challenges in planning for AI-driven demand that can materialize much faster than traditional industrial loads while requiring higher reliability standards.

Studies highlight the interconnected nature of AI energy challenges. Research cited in the International Energy Agency report demonstrates that AI workloads differ fundamentally from traditional computing in their energy consumption patterns. While conventional data center loads follow predictable patterns with daily and weekly cycles, AI training workloads can operate continuously for weeks or months, creating sustained high-demand periods that stress grid infrastructure differently than previous computing workloads.

The SPEC power efficiency research referenced in the IEA analysis shows that server energy efficiency improvements have slowed significantly, making infrastructure expansion rather than efficiency gains the primary response to growing AI demands. This trend suggests that European nations cannot rely on technological efficiency improvements to solve capacity constraints, requiring substantial physical infrastructure investment instead.

European research institutions emphasize the urgent timeline for action. The European Energy Research Alliance analysis indicates that energy system transformation typically requires 15-20 years for complete implementation, while AI adoption accelerates on 2-3 year cycles. This timing mismatch creates a critical window where European competitiveness could be permanently compromised without immediate, coordinated action.

Analysis of transmission tariff structures across Europe, conducted by ENTSO-E (European Network of Transmission System Operators for Electricity), reveals additional complications. Their 2022 overview shows significant variation in how European nations structure transmission costs, creating uneven incentives for data center development and potentially driving AI infrastructure toward countries with more favorable tariff structures rather than optimal geographic locations.

The World Bank’s 2024 research on “Measuring the Emissions & Energy Footprint of the ICT Sector” provides broader context for European challenges. Their analysis indicates that information and communications technology already accounts for approximately 4% of global greenhouse gas emissions, with AI applications potentially doubling this contribution by 2030 without significant efficiency improvements or clean energy transitions.

Research demonstrates that European approaches to AI energy challenges lag global best practices. Studies referenced in the International Energy Agency report show that Asian markets, particularly Singapore and Malaysia, maintain data center connection queues under 3 years through integrated infrastructure planning and expedited permitting processes. European markets’ longer timelines reflect institutional and regulatory complexity that may require fundamental reform rather than incremental improvement.

The cumulative research evidence suggests that Europe faces a systemic challenge requiring coordinated response across energy policy, infrastructure investment, regulatory reform, and skills development. Individual national responses, exemplified by the Netherlands’ experience, appear insufficient to address the scale and speed of AI-driven energy demands that will reshape economic competitiveness over the next decade.

Zsuzsanna Pató, power team lead at the Brussels-based energy NGO RAP, highlighted the warning signs: “There is congestion in other countries,” but other countries should “definitely” see the Dutch example as a warning. A Dutch official acknowledged: “It’s nowhere near as bad anywhere else,” underscoring the Netherlands’ role as an early indicator of European challenges.

Regional analysis exposes infrastructure disparities across Europe. According to the International Energy Agency’s regional breakdown, Europe’s data center electricity consumption grows by more than 45 TWh through 2030, representing a 70% increase from 2024 levels. This growth rate, while lower than the United States’ projected 130% increase, occurs against a backdrop of aging infrastructure and complex regulatory environments that compound implementation challenges.

The research reveals significant variations in European national preparedness. Countries with substantial renewable energy resources, particularly Nordic nations with abundant hydroelectric capacity, maintain competitive advantages for energy-intensive AI applications. However, the geographic concentration of AI infrastructure development in central and western Europe creates mismatches between renewable energy availability and demand centers.

Energy consumption per capita analysis demonstrates European competitive position. The International Energy Agency data shows that European data center consumption per capita remains significantly below United States levels – approximately 100 kWh per capita in 2024 compared to 540 kWh in the United States. While this suggests room for growth, it also indicates European markets’ current infrastructure limitations constrain development relative to economic potential.

Studies document the technical complexity of AI energy integration. Research referenced in the European Energy Research Alliance analysis shows that AI applications for energy system optimization face fundamental challenges from data quality, algorithm transparency, and system integration complexity. These technical barriers compound infrastructure limitations, suggesting that even adequate power supply may not immediately enable optimal AI deployment.

The research indicates that edge computing and distributed AI processing could provide partial solutions to centralized infrastructure constraints. By processing data closer to sources and reducing transmission requirements, edge intelligence applications could reduce pressure on backbone grid infrastructure while maintaining AI capability. However, current implementation remains limited by technical complexity and investment requirements.

Analysis of energy system modeling capabilities reveals European research leadership alongside infrastructure challenges. The European Energy Research Alliance study demonstrates sophisticated understanding of AI integration challenges, yet notes that practical implementation lags theoretical knowledge due to infrastructure and regulatory constraints. This suggests that European institutions possess technical capabilities but lack infrastructure foundations for deployment.

International competitive analysis shows diverging approaches to AI energy challenges. While European markets emphasize regulatory compliance and environmental sustainability, other regions prioritize rapid infrastructure deployment and expedited permitting. The research suggests these different approaches may create lasting competitive advantages for regions that prioritize infrastructure development over regulatory perfection.

The studies collectively indicate that European AI energy challenges extend beyond technical solutions to encompass fundamental questions about economic competitiveness, energy security, and technological sovereignty. The Netherlands experience provides a concrete example of how infrastructure limitations can constrain economic development, potentially serving as either a warning for proactive investment or a preview of continent-wide challenges ahead.

Frankfurt as the digital heart of Europe, and it’s beating slow

Frankfurt faces an unprecedented energy infrastructure crisis that threatens its position as Europe’s premier financial and technology hub. The city’s power grid operators have announced no new capacity allocations until 2030, creating severe bottlenecks for data center expansion and AI deployment at a time when demand is growing exponentially.

Germany’s second-largest data center market is experiencing critical constraints that are forcing businesses to relocate operations, delaying investments, and fundamentally reshaping the competitive landscape. While Frankfurt maintains 745 MW of current data center capacity and remains Europe’s second-largest market after London, the convergence of grid limitations, soaring energy costs, and regulatory complexity is creating a perfect storm for the city’s digital economy.

Frankfurt’s power grid is experiencing unprecedented strain as data center demand continues to surge. The city’s data center market has doubled from approximately 375 MW to 745 MW over the past five years, with an additional 542 MW under construction and 383 MW in planning phases. This explosive growth represents a 39% share of the FLAP-D market (Frankfurt, London, Amsterdam, Paris, Dublin), positioning Frankfurt as Europe’s most concentrated data center hub.

However, this growth has outpaced infrastructure development. Oliver Schiebel, CEO of Mainova WebHouse, Frankfurt’s primary utility provider, confirmed the severity of the situation: “The city’s local grid operators have announced that no new capacities will be allocated in Frankfurt in the next few years and that new allocations will only make sense again under different circumstances. We do not expect the circumstances to change before 2030.”

The infrastructure bottleneck has created a crisis for data center operators and tech companies seeking to establish operations in Frankfurt. Connection delays for new power installations have increased to 3-5 years, with electrical equipment lead times alone often exceeding three years. McKinsey analysis specifically cited Frankfurt and Dublin as markets where “time required to supply power to new data centers can exceed three to five years.”

Frankfurt’s energy challenges are compounded by Germany’s broader energy cost crisis. German data centers face electricity costs over six times higher than European competitors due to taxes, charges, and network fees, with electricity accounting for approximately 50% of operating costs. This cost differential is driving systematic business relocations across Germany.

Major corporations are already acting on these concerns. BASF is shifting operations to the US and China, while Thyssenkrupp is exploring relocation options. Microsoft is building new data centers in the Rheinisches Revier region as an alternative to Frankfurt’s constrained market, while Google established a Berlin-Brandenburg cloud region to overcome Frankfurt’s limitations.

The convergence of energy costs, grid constraints, and regulatory complexity is accelerating business relocations from Frankfurt. Two-thirds of German companies have already relocated operations abroad due to energy challenges, with Frankfurt’s financial and tech sectors particularly vulnerable to these trends. The Frankfurt data center market’s 13.7% inventory growth in 2024 represents a slowdown from 2023’s 20% growth, directly attributable to power supply challenges.

Operational adaptations provide temporary relief. Tennet and regional grid operators offer household contracts discounting electricity used during non-peak times between 11am and 3pm. From April 1, operators can offer contracts barring large industrial users from connections during busy hours in exchange for lower tariffs. The Hague launched a “more conscious use of energy” campaign asking consumers to charge vehicles outside the 4pm-9pm peak period.

Innovation attempts address capacity constraints. Dutch energy ministry and network operators explore methods to safely increase grid loads without causing blackouts similar to the April Iberian peninsula incident. Initiatives include pooling connections and creating “energy hubs” that share grid access among multiple users.

AI development faces energy reality. The contradiction between AI ambitions and energy infrastructure capabilities forces reconsideration of deployment strategies. Countries delivering energy at speed and scale will be best positioned to benefit from AI development, while those with infrastructure limitations may face competitive disadvantages.

The Netherlands situation demonstrates that AI development cannot proceed independently of energy infrastructure planning. As AI-focused data centers can draw electricity equivalent to power-intensive factories like aluminum smelters but concentrate geographically, the challenge differs fundamentally from distributed electrification patterns.

Marketing technology sectors must adapt strategies. The energy constraints affect data processing capabilities that underpin modern advertising technology. Real-time bidding systems, customer data platforms, and AI-powered advertising optimization tools all require consistent power availability that European grids increasingly struggle to provide.

European competitiveness hangs in the balance. The infrastructure limitations could force businesses to relocate AI operations to regions with adequate power supply, potentially undermining Europe’s digital sovereignty objectives. Local leaders express concern that connection queues will drive investment elsewhere, creating long-term economic consequences beyond immediate energy costs.

The Dutch experience serves as Europe’s canary in the coal mine for AI energy demands. Without substantial infrastructure investment and accelerated grid modernization, the continent risks falling behind in the global AI economy. The €200 billion price tag for Dutch grid upgrades alone suggests the magnitude of continent-wide investment required.

As artificial intelligence transforms from experimental technology to essential business infrastructure, Europe’s energy preparedness becomes a determining factor in its technological competitiveness. The Netherlands provides a stark preview of the choices facing every European nation: invest heavily in grid infrastructure or risk exclusion from the AI-driven future.

Timeline

  • 2022PubMatic transitions to 100% renewable energy for global data center operations
  • 2022: EU energy price crisis accelerates company transitions away from gas across Europe
  • 2023: Netherlands ends production at Groningen gasfield, accelerating electrification
  • 2024: Global data center electricity consumption reaches 415 TWh annually
  • 2024: More than 2.6 million Dutch homes install solar panels
  • Policy responses emerge slowly. The EU is consulting on legislation addressing grid upgrade needs and accelerating permitting for grid infrastructure projects before year-end. However, analysts fear minimal immediate relief. “To build a grid takes five to six years. There’s no silver bullet,” Pató explained.
  • November 2024: Gartner predicts power shortages will restrict 40% of AI data centers by 2027
  • 2024Deloitte publishes comprehensive AI environmental footprint study
  • 2024: Goldman Sachs releases analysis on AI data center global power surge and sustainability impact
  • 2024: Electric Power Research Institute conducts utility survey on data center energy trends
  • January 2025: International Energy Agency releases comprehensive Energy and AI report
  • July 13, 2025: Financial Times reports Netherlands rationing electricity amid grid stresses
  • 2025Programmatic advertising growth reaches 72%, increasing data center energy demands
  • April 1, 2025: Dutch operators begin offering contracts restricting industrial users during peak hours
  • 2027: First significant new grid capacity expected in Eindhoven region
  • 2030: Dublin data center connection pause scheduled to end
  • 2034: Dutch electricity tariff increases expected to stabilize
  • 2040: Target completion date for Netherlands €200 billion grid investment



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AI can predict which patients need treatment to preserve their eyesight

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Researchers have successfully used artificial intelligence (AI) to predict which patients need treatment to stabilize their corneas and preserve their eyesight, in a study presented today (Sunday) at the 43rd Congress of the European Society of Cataract and Refractive Surgeons (ESCRS).

The research focused on people with keratoconus, a visual impairment that generally develops in teenagers and young adults and tends to worsen into adulthood. It affects up to 1 in 350 people. In some cases, the condition can be managed with contact lenses, but in others it deteriorates quickly and if it is not treated, patients may need a corneal transplant. Currently the only way to tell who needs treatment is to monitor patients over time.

The researchers used AI to assess images of patients’ eyes, combined with other data, and to successfully predict which patients needed prompt treatment and which could continue with monitoring.

The study was by Dr. Shafi Balal and colleagues at Moorfields Eye Hospital NHS Foundation Trust, London, and University College London (UCL), UK. He said: “In people with keratoconus, the cornea – the eye’s front window – bulges outwards. Keratoconus causes visual impairment in young, working-age patients and it is the most common reason for corneal transplantation in the Western world.

“A single treatment called ‘cross-linking’ can halt disease progression. When performed before permanent scarring develops, cross-linking often prevents the need for corneal transplantation. However, doctors cannot currently predict which patients will progress and require treatment, and which will remain stable with monitoring alone. This means patients need frequent monitoring over many years, with cross-linking typically performed after progression has already occurred.”

The study involved a group of patients who were referred to Moorfields Eye Hospital NHS Foundation Trust for keratoconus assessment and monitoring, including scanning the front of the eye with optical coherence tomography (OCT) to examine its shape. Researchers used AI to study 36,673 OCT images of 6,684 different patients along with other patient data.

The AI algorithm could accurately predict whether a patient’s condition would deteriorate or remain stable using images and data from the first visit alone. Using AI, the researchers could sort two-thirds of patients into a low-risk group, who did not need treatment, and the other third into a high-risk group, who needed prompt cross-linking treatment. When information from a second hospital visit was included, the algorithm could successfully categorise up to 90% of patients.

Cross linking treatment uses ultraviolet light and vitamin B2 (riboflavin) drops to stiffen the cornea, and it is successful in more than 95% of cases.

Our research shows that we can use AI to predict which patients need treatment and which can continue with monitoring. This is the first study of its kind to obtain this level of accuracy in predicting the risk of keratoconus progression from a combination of scans and patient data, and it uses a large cohort of patients monitored over two years or more. Although this study is limited to using one specific OCT device, the research methods and AI algorithm used can be applied to other devices. The algorithm will now undergo further safety testing before it is deployed in the clinical setting.


Our results could mean that patients with high-risk keratoconus will be able to receive preventative treatment before their condition progresses. This will prevent vision loss and avoid the need for corneal transplant surgery with its associated complications and recovery burden. Low-risk patients will avoid unnecessary frequent monitoring, freeing up healthcare resources. The effective sorting of patients by the algorithm will allow specialists to be redirected to areas with the greatest need.”


Dr. Shafi Balal, Moorfields Eye Hospital NHS Foundation Trust

The researchers are now developing a more powerful AI algorithm, trained on millions of eye scans, that can be tailored for specific tasks, including predicting keratoconus progression, but also other tasks such as detecting eye infections and inherited eye diseases.

Dr. José Luis Güell, ESCRS Trustee and Head of the Cornea, Cataract and Refractive Surgery Department at the Instituto de Microcirugía Ocular, Barcelona, Spain, who was not involved in the research, said: “Keratoconus is a manageable condition, but knowing who to treat, and when and how to give treatment is challenging. Unfortunately, this problem can lead to delays, with many patients experiencing vision loss and requiring invasive implant or transplant surgery.

“This research suggests that we can use AI to help predict who will progress, even from their first routine consultation, meaning we could treat patients early before progression and secondary changes. Equally, we could reduce unnecessary monitoring of patients whose condition is stable. If it consistently demonstrates its effectiveness, this technology would ultimately prevent vision loss and more difficult management strategies in young, working-age patients.”



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Billionaire Dan Loeb Just Changed His Mind on This Incredible Artificial Intelligence (AI) Stock

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After eliminating it from his fund’s portfolio in the first quarter, this stock was one of Loeb’s biggest purchases in the second quarter.

Billionaire Dan Loeb is one of the most-followed activist investors on Wall Street. His hedge fund, Third Point, manages $21.1 billion, with around one-third of that invested in a public equity portfolio.

He is supported by a team of over 60 people, but ultimately, Loeb is in charge of the moves in Third Point’s portfolio. He said that by mid-April, he had sold out of most of the “Magnificent Seven” stocks, taking gains off the table early in 2025 before the market crashed amid tariff concerns.

By the end of the first quarter, he’d sold off significant pieces of his stakes in Microsoft and Amazon while completely eliminating positions in Tesla, Apple, and Meta Platforms (META 0.62%). But Loeb was a buyer of most of those again in the second quarter, including Meta. Here’s why Loeb may have changed his mind on the AI leader.

Image source: Getty Images.

Why did Loeb sell Meta in the first place?

Loeb’s decision to sell Meta shares seemed mostly to have been driven by its rising valuations. Shares of Meta reached a forward P/E ratio of 26.5 during the first quarter.

“We realized gains earlier in the year through opportunistic sales near the highs in Meta,” Loeb said in his first-quarter letter to Third Point investors.

It’s very likely that Loeb was concerned about that valuation as uncertainty grew about President Donald Trump’s trade policies. Meta’s core advertising business relies on business confidence. If businesses aren’t confident in their ability to source their products or in the consumer’s willingness to spend, they’re going to be less willing to pay up for advertising on Meta’s apps.

Meanwhile, Meta is investing heavily in artificial intelligence infrastructure. Management said it plans to spend $60 billion to $65 billion on capital expenditures this year, up from $39 billion in 2024. Given the growing uncertainty about what the near-term returns on those investments might be, Loeb took an opportunity to take some money off the table.

Tiptoeing back in

Third Point ended the second quarter with 150,000 shares of Meta. While that only accounted for about 1.5% of its public equity portfolio at the time, it was still enough to make it one of the hedge fund’s biggest purchases in the quarter.

So, what led to the reversal?

It may have been the strong first-quarter earnings report Meta delivered at the end of April. The company saw strong revenue growth, expanded its operating margin, and expressed a lot of confidence about the next quarter and beyond. It raised its capital expenditure plans as well.

Management also made it clear that Meta’s investments in artificial intelligence are already paying off. That assertion was supported by growth in both ad impressions and average price per ad, which it boosted by consistently improving its content and ad recommendation algorithms. The long-term potential for AI to make it easier for marketers to advertise on Meta’s properties and for it to expand advertising opportunities remains a key focus of the company’s spending.

But Meta shares are once again trading at a high valuation. In fact, the stock now carries a higher earnings multiple than it did when Loeb and his team sold the stock in the first quarter.

Should retail investors buy Meta Platforms now?

Meta’s first-quarter results gave investors like Loeb confidence in the stock, and its second-quarter results were arguably even better.

Revenue growth accelerated, and its operating margin expanded once again. The operating margin gains are perhaps the most impressive facet of the narrative, as management has warned about an increase in depreciation expenses from all of its AI investments.

But those AI investments may be the differentiating factor between Meta and other digital advertising platforms. Meta is able to offer marketers higher returns on their ad spending, even while charging them premium prices. As a result, Meta grew its revenue faster than smaller social media platforms did last quarter.

That should give investors confidence that its AI strategy is already paying off. Combine that with the long-term potential for AI to transform the business, and it makes sense for the stock to trade at a premium price. With shares currently trading at just over 27 times expected forward earnings, it may still be underpriced. We won’t know whether or not Loeb took profits once again until November, when Third Point files its next 13F disclosure with the Securities and Exchange Commission. But for most retail investors, Meta shares are worth buying or holding onto right now.

Adam Levy has positions in Amazon, Apple, Meta Platforms, and Microsoft. The Motley Fool has positions in and recommends Amazon, Apple, Meta Platforms, Microsoft, and Tesla. The Motley Fool recommends the following options: long January 2026 $395 calls on Microsoft and short January 2026 $405 calls on Microsoft. The Motley Fool has a disclosure policy.



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Prediction: This Artificial Intelligence (AI) Stock Will Beat Opendoor Technologies over the Next 3 Years

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Opendoor has been on a tear, but this fintech stock looks like a better long-term winner.

Opendoor Technologies (OPEN -13.59%) dazzled investors over the last three months like few other stocks. The online home-flipper jumped an incredible 1,400% over the last three months, going from a little over $0.50 a share to more than $10 at one point.

The rally began with hedge-fund manager Eric Jackson making the case that the stock could be the next Carvana, which jumped to almost 100 times its original price after nearly going bankrupt in 2022. That argument gained steam online and helped turn Opendoor into a meme stock, as it initially surged on high volume and no news.

Since then, the stock gained on real news. That includes the prospect of the Federal Reserve lowering interest rates next week and later in the year, and the company’s board overhauling its management team. In August, embattled CEO Carrie Wheeler stepped down; after hours on Wednesday, Opendoor named Shopify chief operating officer Kaz Nejatian as its new CEO, which sent the stock up 80% on Thursday.

Additionally, the company said that co-founders Keith Rabois and Eric Wu were rejoining the board of directors, and ventures associated with them were investing $40 million into Opendoor. It’s easy to see how that news would inject enthusiasm into the stock, especially after it was on the verge of being delisted by the Nasdaq stock exchange earlier.

However, nothing’s really changed for Opendoor as a business in the last three months. The company never reported a full-year profit, and the business is expected to shrink this quarter due to the weak housing market.

It’s still a high risk with a questionable business model. If you’re looking for a similar stock that can capitalize on falling interest rates, I think that Upstart Holdings (UPST 1.54%) is a better bet, and that it can outperform Opendoor over the next three years.

Image source: Getty Images.

Upstart’s opportunity

Upstart has a number of things in common with Opendoor. Both went public around the same time in 2020, and initially surged out of the gate before plunging in 2022 as interest rates rose and tech stocks crashed.

Upstart is a loan originator. It uses artificial intelligence (AI) technology to screen applicants, producing results it claims are significantly better than traditional FICO scores. Once it creates a loan, it typically sells it to one of its funding partners, so it doesn’t keep the debt on its books.

Like Opendoor’s, Upstart’s business was struggling back in 2022, but the company revamped its business with the help of an improved AI model that increased conversion rates for its loans. Even in a high-interest-rate environment, it’s delivering strong revenue growth. And it’s now profitable based on generally accepted accounting principles (GAAP).

Revenue in the second quarter jumped 102% to $257 million, on a 159% increase in transaction volume. The company reported GAAP net income of $5.6 million, and for the full year, it expects that to be $35 million.

Upstart built its business around consumer loans, but it’s been expanding rapidly into auto and home loans. The home loan market, where it could potentially compete with Opendoor, is massive. In the second quarter, Upstart’s home originations grew nearly 800% from the year-ago quarter to $68 million. That’s still a small fraction of its business, but there’s clearly more growth ahead in the home loan market for Upstart.

Upstart vs. Opendoor

Upstart and Opendoor have similar market caps following Opendoor’s surge. Upstart is valued at $6.1 billion as of Friday, while Opendoor’s market cap is $6.7 billion.

Both companies are also chasing massive addressable markets, and are likely to benefit from lower interest rates.

However, Upstart is the only one of the two that has proven it can grow in a challenging macro environment, and its business now looks set for consistent profitability. At Opendoor, meanwhile, there are real questions about whether home-flipping can scale up as a business model and deliver a consistent profit. Notably, both Zillow Group and Redfin (a subsidiary of Rocket Companies) bowed out of the iBuying competition, finding it too difficult and prone to large losses.

Given those differences, despite the fanfare over Opendoor, Upstart looks like the better bet today. Over the next three years, Upstart looks set to be the winner of the two.

Jeremy Bowman has positions in Carvana, Rocket Companies, Shopify, and Upstart. The Motley Fool has positions in and recommends Shopify, Upstart, and Zillow Group. The Motley Fool recommends Nasdaq and Rocket Companies. The Motley Fool has a disclosure policy.



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