Jobs & Careers
DeepMind Launches AlphaGenome to Predict How DNA Variants Affect Gene Regulation
DeepMind has launched AlphaGenome, a new artificial intelligence (AI) model that can predict how single DNA variants affect gene regulation across the human genome. The model, now available via API for non-commercial research, marks an advance in understanding the genome’s non-coding regions, that is, areas long considered the “dark matter” of DNA.
AlphaGenome can analyse up to 1 million DNA base pairs and delivers high-resolution predictions about thousands of molecular processes, such as where genes begin and end, how RNA is spliced and which proteins bind to DNA. This predictive ability, according to DeepMind, offers a “unifying model” to help scientists better understand gene function and the impact of mutations.
“It’s a milestone for the field,” Dr Caleb Lareau of Memorial Sloan Kettering Cancer Centre said in the blog post. “For the first time, we have a single model that unifies long-range context, base-level precision and state-of-the-art performance across a whole spectrum of genomic tasks.”
Unlike earlier models such as Enformer and AlphaMissense, which focus primarily on protein-coding regions, AlphaGenome is designed to analyse the remaining 98% of the genome, non-coding regions that regulate gene activity and are often linked to disease. DeepMind claims the model offers a new way to explore these vast areas with unprecedented detail.
The architecture combines convolutional layers to detect short patterns, transformer models to capture long-range dependencies and final layers to produce predictions. According to the company, AlphaGenome outperformed top external models in 22 of 24 sequence prediction benchmarks and matched or exceeded others in 24 of 26 variant-effect tasks.
In a test case involving T-cell acute lymphoblastic leukaemia (T-ALL), AlphaGenome successfully predicted how specific mutations activate the cancer-related TAL1 gene by creating a new binding site for the MYB protein, replicating a known disease mechanism. The result underscored the model’s potential to link non-coding variants to disease outcomes.
“AlphaGenome will be a powerful tool for the field,” Professor Marc Mansour of University College London explained in the post. “Determining the relevance of different non-coding variants can be extremely challenging, particularly to do at scale. This tool provides a crucial piece of the puzzle.”
DeepMind acknowledges some limitations. It still struggles with predicting the effects of very distant DNA interactions, over 1 lakh letters apart, and has not been validated for personal genome interpretation or clinical use.
Researchers are invited to access AlphaGenome through its preview API and collaborate via DeepMind’s community forum. The company says the model could accelerate discovery across disease research, synthetic biology, and basic science.
“We hope AlphaGenome will deepen our understanding of the complex cellular processes encoded in the DNA sequence and drive exciting new discoveries in genomics and healthcare,” DeepMind said in a statement.
Tata Consultancy Services (TCS) has been selected by the Odisha government to design and implement Integrated Financial Management System (IFMS) 3.0, an AI-enabled, cloud-native platform to modernise the state’s public finance management.
The new system will automate Odisha’s finance workflows using microservices-based architecture and integrate TCS’s AI Workbench (AIWB), which supports AI/ML projects across development, monitoring, and retraining.
Features will include AI-driven analytics, multilingual chatbot support, and automated service desk functions to improve efficiency and user experience.
Key features of IFMS 3.0 include a user-friendly interface for easier navigation, real-time integration of financial data across departments, advanced reporting and analytics tools, stronger security protocols to ensure compliance, and mobile accessibility that enables users to manage financial operations on the go.
TCS has partnered with Odisha since 2005, beginning with the state’s Treasury Management System, followed by IFMS and IFMS 2.0. This third-generation upgrade aims to provide real-time visibility, enhance data accuracy, and streamline processes across budgeting, expenditure, revenue, and accounts management.
“With real-time financial visibility, enhanced precision, and a future-ready architecture, this platform will empower Odisha to deliver more effective public services to its citizens,” Girish Ramachandran, president, growth markets and public services, TCS said.
“With AI-assisted insights and intuitive workflows, IFMS 3.0 will allow officials to monitor programs in real time, accelerate reporting, and make confident, data-driven decisions,” Tej Paul Bhatla, VP, public services, TCS said.
This initiative is part of TCS’s broader role in India’s digital transformation. For nearly six decades, TCS has been a technology partner to government programs, helping digitise services such as passport issuance, defence pensions, health insurance, and public financial systems. Nearly seven out of ten Indians use TCS-supported services daily.
The post TCS to Develop AI-Powered Financial System for Odisha Govt appeared first on Analytics India Magazine.
Jobs & Careers
6 in 10 Firms Expect AI to Act as Teammate or Supervisor to Other AI Systems by Mid-2026: Capgemini Report
Nearly six in 10 enterprises expect AI to function as a team member or supervisor for other AI systems within 12 months, according to the latest annual study from the Capgemini Research Institute.
The report, titled ‘Harnessing the Value of AI: Unlocking Scalable Advantage’, also mentions that the adoption of generative AI is outpacing organisational readiness, which is sparking challenges in cost, governance, and workforce adaptation.
The findings further reveal that one-third of organisations are now fully or partially scaling generative AI, compared with just 6% in 2023, a five-fold surge in two years.
About 93% of the survey companies said they are either piloting, deploying, or enabling AI capabilities in 2025, with sectors such as telecom, consumer products, and ae
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OpenAI is moving into the hiring and training space with the launch of a Jobs Platform and new AI Certifications, aiming to connect millions of workers with employers and reshape how companies hire AI-savvy talent.
The company stated that the OpenAI Jobs Platform will serve as a marketplace where businesses can find workers trained in AI, while job seekers can showcase their verified skills. Unlike traditional hiring platforms, it will cater not only to large corporations but also to local businesses and governments looking for AI talent.
OpenAI is collaborating with a diverse network of partners for the same, including Walmart, John Deere, Boston Consulting Group, Accenture, Indeed, Texas Association of Business, Bay Area Council and Delaware Governor’s Office.
Meanwhile, OpenAI Certifications builds on the free OpenAI Academy, which has already reached over two million learners. OpenAI plans to certify 10 million Americans by 2030 in AI fluency, from basic workplace use to advanced prompt engineering.
Preparation and testing will take place inside ChatGPT itself. Walmart, the world’s largest private employer, is among the launch partners.
“At Walmart, we know the future of retail won’t be defined by technology alone—it will be defined by people who know how to use it,” John Furner, CEO of Walmart US, said in a statement.
The company says that the aim is to give more people economic opportunities as AI transforms work. “It’s all about being intentional about the kind of future we want to build,” the statement read, adding that the focus is on making AI literacy accessible and useful for both workers and employers.
The initiatives are also a part of OpenAI’s commitment to the White House’s AI literacy push. With hundreds of millions already using ChatGPT weekly, OpenAI believes its next big move lies in jobs and skills territory traditionally dominated by hiring and training platforms.
The post OpenAI Expands Beyond ChatGPT With New Jobs Platform, AI Skills Certification appeared first on Analytics India Magazine.
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