At the European conference of the Pistoia Alliance, a global nonprofit, early in 2025, a theme emerged: that agentic artificial intelligence (AI) is viewed by life sciences professionals as potentially being among the most disruptive emerging technologies over the next two to three years (1). Agentic AI has the potential, according to the Pistoia Alliance, to accelerate multi-step processes, such as target prioritization and compound optimization, by joining together reasoning, tool use, and execution.

However, the Pistoia Alliance said in a Sept. 4, 2025 press release that surrendering full autonomy to AI creates a sort of “black box” that may undermine trust, capacity for reproducibility, and regulatory compliance (1). It is for those reasons—with the overarching mission of safely adopting agentic AI—that the nonprofit is establishing a new initiative bringing together experts from the pharmaceutical, technology, and biotech industries to help shape certain standards and protocols under which AI agents will be allowed to perform.

How will the initiative encourage responsible AI use?

With Genentech providing the initial seed funding for the project, the Pistoia Alliance said it is currently seeking both additional partners and funds (1). The nonprofit has stated strategic priorities to harness AI and expedite R&D and is calling upon an AI and machine learning (ML) community of experts to continue building support for the industry-wide responsible adoption of AI.

“Our members see agentic AI as one of the most impactful technologies set to change how they work and innovate, but they also recognize the risks if adoption happens without the right guardrails,” said Becky Upton, PhD, president of the Pistoia Alliance, in the press release (1). “The Alliance is uniquely positioned to lead this work, drawing on more than eight years’ experience in pre-competitive collaboration around AI, from benchmarking frameworks for large language models to a pharmacovigilance community focused on responsible AI deployment. We know that more expert minds focused on the same topic will advance the safe and successful use of AI technologies.”

What are priorities for the industry?

As part of a recent webinar, the Pistoia Alliance said it polled more than 100 pharma professionals, and the consensus top priority for pre-competitive collaboration was the creation of shared validation frameworks and metrics, for model robustness and bias (1). Shared frameworks urgently need to be established, according to the Pistoia Alliance, for the safe adoption of AI because when evidence must be validated, auditable agent workflows that are shaped by subject matter experts and reputable data sources are necessary for the production of reliable results.

“This initiative will address the common issues we all face in integrating AI developments into a cohesive ecosystem that improves output quality,” said Robert Gill, the Agentic AI program lead at the Pistoia Alliance, in the press release (1). “It will enable members to link standalone AI applications into a dynamic network and build workflows where multiple agents can reason, plan and act together. By becoming sponsors, organizations can act as first movers—shaping the standards, gaining early access to outputs, and ensuring they are at the forefront of the next wave of AI innovation in healthcare.”

Want to make your voice heard?

Pharmaceutical Technology® Group is asking its audience within the bio/pharmaceutical industry to share their experiences in a survey that seeks perspectives on new and rapidly evolving technologies as automation, advanced analytics, digital twins, and AI (2). The survey can be accessed directly at this link.

References

1. Pistoia Alliance. Pistoia Alliance Unveils Agentic AI Initiative and Seeks Industry Funding to Drive Safe Adoption. Press Release. Sept. 4, 2025.
2. Cole, C. Digital Transformation in Pharma Manufacturing: Industry Perspectives Survey. PharmTech.com, Aug. 27, 2025.

At the European conference of the Pistoia Alliance, a global nonprofit, early in 2025, a theme emerged: that agentic artificial intelligence (AI) is viewed by life sciences professionals as potentially being among the most disruptive emerging technologies over the next two to three years (1). Agentic AI has the potential, according to the Pistoia Alliance, to accelerate multi-step processes, such as target prioritization and compound optimization, by joining together reasoning, tool use, and execution.

However, the Pistoia Alliance said in a Sept. 4, 2025 press release that surrendering full autonomy to AI creates a sort of “black box” that may undermine trust, capacity for reproducibility, and regulatory compliance (1). It is for those reasons—with the overarching mission of safely adopting agentic AI—that the nonprofit is establishing a new initiative bringing together experts from the pharmaceutical, technology, and biotech industries to help shape certain standards and protocols under which AI agents will be allowed to perform.

How will the initiative encourage responsible AI use?

With Genentech providing the initial seed funding for the project, the Pistoia Alliance said it is currently seeking both additional partners and funds (1). The nonprofit has stated strategic priorities to harness AI and expedite R&D and is calling upon an AI and machine learning (ML) community of experts to continue building support for the industry-wide responsible adoption of AI.

“Our members see agentic AI as one of the most impactful technologies set to change how they work and innovate, but they also recognize the risks if adoption happens without the right guardrails,” said Becky Upton, PhD, president of the Pistoia Alliance, in the press release (1). “The Alliance is uniquely positioned to lead this work, drawing on more than eight years’ experience in pre-competitive collaboration around AI, from benchmarking frameworks for large language models to a pharmacovigilance community focused on responsible AI deployment. We know that more expert minds focused on the same topic will advance the safe and successful use of AI technologies.”

What are priorities for the industry?

As part of a recent webinar, the Pistoia Alliance said it polled more than 100 pharma professionals, and the consensus top priority for pre-competitive collaboration was the creation of shared validation frameworks and metrics, for model robustness and bias (1). Shared frameworks urgently need to be established, according to the Pistoia Alliance, for the safe adoption of AI because when evidence must be validated, auditable agent workflows that are shaped by subject matter experts and reputable data sources are necessary for the production of reliable results.

“This initiative will address the common issues we all face in integrating AI developments into a cohesive ecosystem that improves output quality,” said Robert Gill, the Agentic AI program lead at the Pistoia Alliance, in the press release (1). “It will enable members to link standalone AI applications into a dynamic network and build workflows where multiple agents can reason, plan and act together. By becoming sponsors, organizations can act as first movers—shaping the standards, gaining early access to outputs, and ensuring they are at the forefront of the next wave of AI innovation in healthcare.”

Want to make your voice heard?

Pharmaceutical Technology® Group is asking its audience within the bio/pharmaceutical industry to share their experiences in a survey that seeks perspectives on new and rapidly evolving technologies as automation, advanced analytics, digital twins, and AI (2). The survey can be accessed directly at this link.

References

1. Pistoia Alliance. Pistoia Alliance Unveils Agentic AI Initiative and Seeks Industry Funding to Drive Safe Adoption. Press Release. Sept. 4, 2025.
2. Cole, C. Digital Transformation in Pharma Manufacturing: Industry Perspectives Survey. PharmTech.com, Aug. 27, 2025.

The luxury membership platform Vivrelle, which allows customers to rent high-end goods, announced Thursday the launch of an AI personal styling tool called Ella as part of its partnership with fashion retailers Revolve and FWRD.

The launch is an example of how the fashion industry is leveraging AI technology to enhance customer experiences and is one of the first partnerships to see three retailers come together to offer a personalized AI experience. Revolve and FWRD let users shop designer clothing, while Revolve also has an option to shop pre-owned.

The tool, Ella, provides recommendations to customers across the three retailers on what to purchase or rent to make an outfit come to life. For example, users can ask for “a bachelorette weekend outfit,” or “what to pack for a trip,” and the technology will search across the Vivrelle, FWRD, and Revolve shopping platforms to create outfit suggestions. Users can then check out in one cart on Vivrelle.

In theory, the more one uses Ella, the better its suggestions become. It’s the fashion equivalent of asking ChatGPT what to wear in Miami for a girl’s weekend.

Blake Geffen, the CEO and co-founder of Vivrelle (which announced a $62 million Series C earlier this year), told TechCrunch that she hopes Ella can take the “stress out of packing for a vacation or everyday dressing.

“Ella has been in the works for quite some time,” she told TechCrunch, adding that it took about a year to build and release the product. 

This is actually the second AI tool from the three companies. The Vivrelle, Revolve, and FWRD partnership earlier this year also launched Complete the Look, which offers last-minute fashion suggestions to complement what’s in a customer’s cart at checkout. Their latest tool, Ella, however, takes the fashion recommendation game to another level.

Fashion has been obsessed with trying to make personalized shopping happen for decades now. Even the 90s movie “Clueless” showed Cher picking outfits from her digitized wardrobe.

This current AI boom has led to rapid innovation and democratized access to AI technology, allowing many fashion companies to launch personalized AI fashion companies and raise millions while doing so.

“With Ella, we’re giving our members as much flexibility and options as possible to shop or borrow with ease, through seamless conversations that allow you to share as little or as much as you want, just like talking to a live stylist,” Geffen said. “We’re excited to be the first brand to integrate rental, resale, and retail into one streamlined omnichannel experience.”