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Artificial intelligence set to transform mental health care for breast cancer patients

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From virtual counselors that can hear depression creeping into a person’s voice to smart watches that can detect stress, artificial intelligence is poised to revolutionize mental health care for patients with breast cancer.

In a new paper, UVA Cancer Center’s J. Kim Penberthy, PhD, and colleagues detail the many ways artificial intelligence could help ensure patients receive the support they need. AI, they say, can identify patients at risk for mental-health struggles, get them treatment earlier, provide continuous psychological monitoring and even perform personalized interventions tailored to the individual.

But that’s just the tip of the iceberg. AI, the researchers say, can overcome some of the biggest barriers patients face to getting mental-health support by expanding options beyond clinic walls and delivering care exactly where and when it’s needed – even to rural areas where patients lack local mental-health treatment options.

Soon, doctors may combine multiple AI technologies to provide patients a “holistic, interactive treatment experience” that ensures the mental-health support is every bit as good as the care for the cancer itself, the UVA researchers write.

AI can help us notice when a patient is struggling and get them the right support faster,” said Penberthy, a clinical psychologist at UVA Health and UVA Cancer Center. This technology is moving quickly, and it’s exciting to see how soon it could make a real difference in people’s lives.

Breast cancer and mental health

Breast cancer is the most common cancer in women, with 2.3 million new diagnoses each year. Up to half of those patients will go on to experience anxiety, depression or post-traumatic stress disorder (PTSD). While there have been great advances in how we treat breast cancer, mental-health support for these patients has lagged behind, the UVA researchers note.

Mental health care is a lifeline for women with breast cancer,” Penberthy said. “Up to half experience anxiety or depression, and without support, treatment and quality of life can suffer. AI can help spot distress early and connect women to the care they need.

The co-authors envision a future – a near future – where AI plays a vast and crucial role in supporting patients’ mental health. The technology, they say, should not replace clinicians and care providers, but instead can extend providers’ reach and presence. By monitoring patients in real time, for example, AI could alert doctors that a patient may be struggling or slipping into depression.

Similarly, AI-powered chatbots and telepsychiatry platforms offer “scalable, cost-effective solutions” to increase access to psychological care, the researchers write. These advanced AI chatbots go far beyond the simple conversations often associated with their ilk. Instead of just responding to straightforward questions, the electronic entities can provide on-demand emotional support, suggest coping mechanisms, detail relaxation techniques and offer continuous psychological support even when therapists are unavailable.

AI, the researchers write, has tremendous potential to improve “accessibility, personalization, efficiency and cost-effectiveness of mental health care for patients with breast cancer. But they caution that the technology also brings challenges and ethical considerations. For example, AI can be a powerful tool to analyze mental health data, but this requires strict safeguards to protect patient privacy. Similarly, studies have shown that AI can “underperform” for patients from minority or underrepresented backgrounds, potentially contributing to care disparities, the authors write. 

Those are the type of things that doctors and researchers will have to keep in mind as they explore the potential of AI, Penberthy and her collaborators say. But they are excited for what the future holds, noting that AI has “immense” potential for improving mental health support for patients with breast cancer.

We’re just beginning to scratch the surface of AI’s potential in health care and the positive impact AI will have in our lives. I’m incredibly optimistic about what the future will bring!” 


David Penberthy, MD, MBA, co-author

UVA’s cutting-edge cancer research

Finding new ways to improve patient care is a core mission of both UVA Cancer Center and UVA’s Paul and Diane Manning Institute of Biotechnology. UVA Cancer Center is one of only 57 cancer centers in the country designated “comprehensive” by the National Cancer Institute in recognition of their exceptional patient care and cutting-edge cancer research.

The Manning Institute, meanwhile, has been launched to accelerate the development of new treatment and cures for the most challenging diseases. This will be complemented by a statewide clinical trials network that expands access to potential new treatments as they are developed and tested.

AI paper published

The Penberthys and their co-author – Jennifer Bires, MSW, LCSW, OSW-C – have published their paper in the scientific journal AI in Precision Oncology.

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Journal reference:

Kim Penberthy, J., et al. (2025) A Narrative Review of the Role of Artificial Intelligence in Supporting the Mental Health of Patients with Breast Cancer. AI in Precision Oncology. https://doi.org/10.1177/2993091X251361147.



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Physicians Lose Cancer Detection Skills After Using Artificial Intelligence

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Artificial intelligence shows great promise in helping physicians improve both their diagnostic accuracy of important patient conditions. In the realm of gastroenterology, AI has been shown to help human physicians better detect small polyps (adenomas) during colonoscopy. Although adenomas are not yet cancerous, they are at risk for turning into cancer. Thus, early detection and removal of adenomas during routine colonoscopy can reduce patient risk of developing future colon cancers.

But as physicians become more accustomed to AI assistance, what happens when they no longer have access to AI support? A recent European study has shown that physicians’ skills in detecting adenomas can deteriorate significantly after they become reliant on AI.

The European researchers tracked the results of over 1400 colonoscopies performed in four different medical centers. They measured the adenoma detection rate (ADR) for physicians working normally without AI vs. those who used AI to help them detect adenomas during the procedure. In addition, they also tracked the ADR of the physicians who had used AI regularly for three months, then resumed performing colonoscopies without AI assistance.

The researchers found that the ADR before AI assistance was 28% and with AI assistance was 28.4%. (This was a slight increase, but not statistically significant.) However, when physicians accustomed to AI assistance ceased using AI, their ADR fell significantly to 22.4%. Assuming the patients in the various study groups were medically similar, that suggests that physicians accustomed to AI support might miss over a fifth of adenomas without computer assistance!

This is the first published example of so-called medical “deskilling” caused by routine use of AI. The study authors summarized their findings as follows: “We assume that continuous exposure to decision support systems such as AI might lead to the natural human tendency to over-rely on their recommendations, leading to clinicians becoming less motivated, less focused, and less responsible when making cognitive decisions without AI assistance.”

Consider the following non-medical analogy: Suppose self-driving car technology advanced to the point that cars could safely decide when to accelerate, brake, turn, change lanes, and avoid sudden unexpected obstacles. If you relied on self-driving technology for several months, then suddenly had to drive without AI assistance, would you lose some of your driving skills?

Although this particular study took place in the field of gastroenterology, I would not be surprised if we eventually learn of similar AI-related deskilling in other branches of medicine, such as radiology. At present, radiologists do not routinely use AI while reading mammograms to detect early breast cancers. But when AI becomes approved for routine use, I can imagine that human radiologists could succumb to a similar performance loss if they were suddenly required to work without AI support.

I anticipate more studies will be performed to investigate the issue of deskilling across multiple medical specialties. Physicians, policymakers, and the general public will want to ask the following questions:

1) As AI becomes more routinely adopted, how are we tracking patient outcomes (and physician error rates) before AI, after routine AI use, and whenever AI is discontinued?

2) How long does the deskilling effect last? What methods can help physicians minimize deskilling, and/or recover lost skills most quickly?

3) Can AI be implemented in medical practice in a way that augments physician capabilities without deskilling?

Deskilling is not always bad. My 6th grade schoolteacher kept telling us that we needed to learn long division because we wouldn’t always have a calculator with us. But because of the ubiquity of smartphones and spreadsheets, I haven’t done long division with pencil and paper in decades!

I do not see AI completely replacing human physicians, at least not for several years. Thus, it will be incumbent on the technology and medical communities to discover and develop best practices that optimize patient outcomes without endangering patients through deskilling. This will be one of the many interesting and important challenges facing physicians in the era of AI.



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AI exposes 1,000+ fake science journals

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A team of computer scientists led by the University of Colorado Boulder has developed a new artificial intelligence platform that automatically seeks out “questionable” scientific journals.

The study, published Aug. 27 in the journal “Science Advances,” tackles an alarming trend in the world of research.

Daniel Acuña, lead author of the study and associate professor in the Department of Computer Science, gets a reminder of that several times a week in his email inbox: These spam messages come from people who purport to be editors at scientific journals, usually ones Acuña has never heard of, and offer to publish his papers — for a hefty fee.

Such publications are sometimes referred to as “predatory” journals. They target scientists, convincing them to pay hundreds or even thousands of dollars to publish their research without proper vetting.

“There has been a growing effort among scientists and organizations to vet these journals,” Acuña said. “But it’s like whack-a-mole. You catch one, and then another appears, usually from the same company. They just create a new website and come up with a new name.”

His group’s new AI tool automatically screens scientific journals, evaluating their websites and other online data for certain criteria: Do the journals have an editorial board featuring established researchers? Do their websites contain a lot of grammatical errors?

Acuña emphasizes that the tool isn’t perfect. Ultimately, he thinks human experts, not machines, should make the final call on whether a journal is reputable.

But in an era when prominent figures are questioning the legitimacy of science, stopping the spread of questionable publications has become more important than ever before, he said.

“In science, you don’t start from scratch. You build on top of the research of others,” Acuña said. “So if the foundation of that tower crumbles, then the entire thing collapses.”

The shake down

When scientists submit a new study to a reputable publication, that study usually undergoes a practice called peer review. Outside experts read the study and evaluate it for quality — or, at least, that’s the goal.

A growing number of companies have sought to circumvent that process to turn a profit. In 2009, Jeffrey Beall, a librarian at CU Denver, coined the phrase “predatory” journals to describe these publications.

Often, they target researchers outside of the United States and Europe, such as in China, India and Iran — countries where scientific institutions may be young, and the pressure and incentives for researchers to publish are high.

“They will say, ‘If you pay $500 or $1,000, we will review your paper,'” Acuña said. “In reality, they don’t provide any service. They just take the PDF and post it on their website.”

A few different groups have sought to curb the practice. Among them is a nonprofit organization called the Directory of Open Access Journals (DOAJ). Since 2003, volunteers at the DOAJ have flagged thousands of journals as suspicious based on six criteria. (Reputable publications, for example, tend to include a detailed description of their peer review policies on their websites.)

But keeping pace with the spread of those publications has been daunting for humans.

To speed up the process, Acuña and his colleagues turned to AI. The team trained its system using the DOAJ’s data, then asked the AI to sift through a list of nearly 15,200 open-access journals on the internet.

Among those journals, the AI initially flagged more than 1,400 as potentially problematic.

Acuña and his colleagues asked human experts to review a subset of the suspicious journals. The AI made mistakes, according to the humans, flagging an estimated 350 publications as questionable when they were likely legitimate. That still left more than 1,000 journals that the researchers identified as questionable.

“I think this should be used as a helper to prescreen large numbers of journals,” he said. “But human professionals should do the final analysis.”

A firewall for science

Acuña added that the researchers didn’t want their system to be a “black box” like some other AI platforms.

“With ChatGPT, for example, you often don’t understand why it’s suggesting something,” Acuña said. “We tried to make ours as interpretable as possible.”

The team discovered, for example, that questionable journals published an unusually high number of articles. They also included authors with a larger number of affiliations than more legitimate journals, and authors who cited their own research, rather than the research of other scientists, to an unusually high level.

The new AI system isn’t publicly accessible, but the researchers hope to make it available to universities and publishing companies soon. Acuña sees the tool as one way that researchers can protect their fields from bad data — what he calls a “firewall for science.”

“As a computer scientist, I often give the example of when a new smartphone comes out,” he said. “We know the phone’s software will have flaws, and we expect bug fixes to come in the future. We should probably do the same with science.”

Co-authors on the study included Han Zhuang at the Eastern Institute of Technology in China and Lizheng Liang at Syracuse University in the United States.



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Pixel Magic Cue AI: Google’s Latest Productivity Play

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Pixel Magic Cue AI is Google’s latest strategic play to embed proactive, time-saving intelligence directly into the Pixel experience, fundamentally reshaping mobile productivity.

Google is doubling down on ambient intelligence, and its latest move, the Pixel Magic Cue AI, aims to fundamentally reshape how users interact with their devices for everyday productivity. This isn’t just another feature; it’s a strategic push to embed AI deeper into the Pixel experience, making the phone a proactive assistant rather than a reactive tool.

The premise is simple: anticipate user needs, streamline tasks, and cut down on decision fatigue. According to the announcement, the Pixel Magic Cue AI is designed to save users significant time by intelligently managing information and actions across the device. This positions Google squarely in the ongoing race among tech giants to deliver truly useful on-device AI, moving beyond flashy demos to tangible, daily benefits.

One of the core promises of Magic Cue AI is its ability to distill complex information. Imagine receiving a lengthy email thread or a dense document. Instead of sifting through paragraphs, Magic Cue can provide a concise summary, highlighting key points and action items. This isn’t just about speed reading; it’s about intelligent extraction, allowing users to grasp the essence of communications without the cognitive load. For professionals drowning in digital noise, this could be a game-changer, freeing up mental bandwidth for more critical tasks.

Beyond Summaries: Proactive Assistance

The AI’s capabilities extend far beyond text summarization. It’s engineered to anticipate your next move. For instance, if you’re planning a trip, Magic Cue AI can automatically pull flight details from your emails, suggest local attractions based on your calendar, and even pre-fill forms for hotel check-ins. This level of predictive assistance moves the Pixel from a device you operate to a partner that understands your context and helps you navigate your day with minimal friction. It’s a subtle but powerful shift towards a truly ambient computing experience, where the technology fades into the background, leaving you to focus on the task at hand.

Another significant time-saver comes in managing notifications and communications. Magic Cue AI can intelligently prioritize alerts, group related messages, and even draft quick replies based on context and your communication style. This isn’t just about silencing your phone; it’s about ensuring you see what’s important when it’s important, and providing tools to respond efficiently without getting bogged down in trivial interactions. The implications for digital well-being are substantial, potentially reducing the constant pull of notifications that often fragment our attention.

Finally, the Pixel Magic Cue AI aims to simplify device management itself. From optimizing battery life based on usage patterns to suggesting app shortcuts for frequently performed actions, the AI learns and adapts to your habits. This continuous optimization means less time spent tweaking settings and more time using your phone effectively. It’s Google’s vision of a smartphone that truly understands its owner, making the device feel less like a gadget and more like an extension of your own productivity.

The rollout of Pixel Magic Cue AI isn’t just about adding new features; it’s about Google’s long-term strategy to differentiate its hardware through intelligent software. As AI becomes increasingly commoditized, the real battle will be in how seamlessly and intuitively it integrates into daily life. Magic Cue represents a significant step in that direction, setting a new bar for what users can expect from their mobile devices and pushing the industry further into an era of truly proactive, context-aware computing.



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