TAMPA, Fla. – Researchers are looking to use artificial intelligence to detect when a baby is in pain.

The backstory:

A baby’s cry is enough to alert anyone that something’s wrong. But for some of the most critical babies in hospital care, they can’t cry when they are hurting.

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“As a bedside nurse, it is very hard. You are trying to read from the signals from the baby,” said Marcia Kneusel, a clinical research nurse with TGH and USF Muma NICU.

With more than 20 years working in the neonatal intensive care unit, Kneusel said nurses read vital signs and rely on their experience to care for the infants.

“However, it really, it’s not as clearly defined as if you had a machine that could do that for you,” she said.

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Big picture view:

That’s where a study by the University of South Florida comes in. USF is working with TGH to develop artificial intelligence to detect a baby’s pain in real-time.

“We’re going to have a camera system basically facing the infant. And the camera system will be able to look at the facial expression, body motion, and hear the crying sound, and also getting the vital signal,” said Yu Sun, a robotics and AI professor at USF.

Yu heads up research on USF’s AI study, and he said it’s part of a two-year $1.2 million National Institutes of Health grant.

He said the study will capture data by recording video of the babies before a procedure for a baseline. Video will record the babies for 72 hours after the procedure, then be loaded into a computer to create the AI program. It will help tell the computer how to use the same basic signals a nurse looks at to pinpoint pain.

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“Then there’s alarm will be sent to the nurse, the nurse will come and check the situation, decide how to treat the pain,” said Sun.

What they’re saying:

Kneusel said there’s been a lot of change over the years in the NICU world with how medical professionals handle infant pain.

“There was a time period we just gave lots of meds, and then we realized that that wasn’t a good thing. And so we switched to as many non-pharmacological agents as we could, but then, you know, our baby’s in pain. So, I’ve seen a lot of change,” said Kneusel.

Why you should care:

Nurses like Kneusel said the study could change their care for the better.

“I’ve been in this world for a long time, and these babies are dear to me. You really don’t want to see them in pain, and you don’t want to do anything that isn’t in their best interest,” said Kneusel.

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USF said there are 120 babies participating in the study, not just at TGH but also at Stanford University Hospital in California and Inova Hospital in Virginia.

What’s next:

Sun said the study is in the first phase of gathering the technological data and developing the AI model. The next phase will be clinical trials for real world testing in hospital settings, and it would be through a $4 million NIH grant, Sun said.

The new offering is designed for controllers, helping them to automatically enforce company expense policies, block unauthorized spending, and stop fraud, and is the first in a series of agents slated for release this year, the company said in a Thursday (July 10) news release.

“Finance teams are being asked to do more with less, yet the function remains largely manual,” Ramp said in the release. “Teams using legacy platforms today spend up to 70% of their time on tasks like expense review, policy enforcement, and compliance audits. As a result, 59% of professionals in controllership roles report making several errors each month.”

Ramp says its controller-centric agents solve these issues by doing away with redundant tasks, and working autonomously to go over expenses and enforce policy, applying “context-aware, human-like” reasoning to manage entire workflows on their own.

“Unlike traditional automation that relies on basic rules and conditional logic, these agents reason and act on behalf of the finance team, working independently to enforce spend policies at scale, immediately prevent violations, and continuously improve company spending guidelines,” the release added.

PYMNTS wrote earlier this week about the “promise of agentic AI,” systems that not only generate content or parse data, but move beyond passive tasks to make decisions, initiate workflows and even interact with other software to complete projects.

“It’s AI not just with brains, but with agency,” that report said.

Industries including finance, logistics and healthcare are using these tools for things like booking meetings, processing invoices or managing entire workflows autonomously.

But although some corporate leaders might hold lofty views for autonomous AI, the latest PYMNTS Intelligence in the June 2025 CAIO Report, “AI at the Crossroads: Agentic Ambitions Meet Operational Realities,” shows a trust gap among executives when it comes to agentic AI that highlights serious concerns about accountability and compliance.

“However, full-scale enterprise adoption remains limited,” PYMNTS wrote. “Despite growing capabilities, agentic AI is being deployed in experimental or limited pilot settings, with the majority of systems operating under human supervision.”

But what makes mid-market companies uneasy about tapping into the power of autonomous AI? The answer is strategic and psychological, PYMNTS added, noting that while the technological potential is enormous, the readiness of systems (and humans) is much murkier.

“For AI to take action autonomously, executives must trust not just the output, but the entire decision-making process behind it. That trust is hard to earn — and easy to lose,” PYMNTS wrote, noting that the research “found that 80% of high-automation enterprises cite data security and privacy as their top concern with agentic AI.”