AI Research
Researchers develop more precise new AI tool to predict risk of heart attack
Researchers from The University of Western Australia, working with medtech industry partners Artrya, have developed a new, fully automated AI algorithm that is more effective than current methods at predicting the risk of heart attack.
First author Dr Gavin Huangfu, from UWA’s Medical School, Harry Perkins Institute of Medical Research and Fiona Stanley Hospital, said coronary artery calcium scoring had revolutionised the prevention of heart disease in those with no symptoms, but the way it was measured had inherent drawbacks.
“It does not account for the location of calcified plaques along the coronary arteries despite knowledge that disease near the start of the artery carries greater risk,” Dr Huangfu said.
“Also, highly calcified plaques are assigned paradoxically higher risk, although are otherwise considered stable plaques and actually confer lower risk of cardiac events such heart attack or sudden death due to heart attack.
“Solutions to these flaws require analysis of each individual plaque, which is not feasible for a human investigator, but readily attainable using artificial intelligence.”
The team found the algorithm, known as CAC-DAD score, was capable of measuring the burden of coronary calcification as well as each lesion’s distance from the coronary artery origin and reclassifying highly dense plaque as low risk – all done with a single click.
“We found that the CAC-DAD score is more precise and effective than the standard Agatston score at predicting the risk of cardiac events, particularly around the time of surgery, in vulnerable populations,” Dr Huangfu said.
“We also found the combined use of Agatston score and CAC-DAD score together further improved risk prediction, opening many possibilities for its clinical use.”
Senior author Professor Girish Dwivedi, also from UWA’s Medical School, said heart disease remained the leading cause of death in developed countries.
“The optimal treatment remains prevention, which relies on accurate risk stratification to identify those at greatest risk who should receive targeted and aggressive preventative measures,” Professor Dwivedi said.
“Your calcium score is the single, greatest predictor for your risk of having a first heart attack and optimising its accuracy will have significant benefits for the management of your risk.
“The shift to personalised care is a necessity and requires personalised investigations on top of population-based clinical risk scores.
“The greatest benefit of calcium scoring is its wide ease of applicability and interpretation. Once validated in other studies, our simple, yet powerful output of the CAC-DAD score can be used to guide management of patients by all members of the medical community.
“From here, we look forward to examining and validating the predictive power of the CAC-DAD score in larger, international cohorts.”
The project was made possible by the collaboration between UWA, Artrya Ltd, South Metropolitan Health Service, Harry Perkins Institute of Medical Research, Victor Chang Cardiac Research Institute, the University of Ottawa Heart Institute in Canda and international efforts from the Vision group.
AI Research
Indonesia on Track to Achieve Sovereign AI Goals With NVIDIA, Cisco and IOH
As one of the world’s largest emerging markets, Indonesia is making strides toward its “Golden 2045 Vision” — an initiative tapping digital technologies and bringing together government, enterprises, startups and higher education to enhance productivity, efficiency and innovation across industries.
Building out the nation’s AI infrastructure is a crucial part of this plan.
That’s why Indonesian telecommunications leader Indosat Ooredoo Hutchison, aka Indosat or IOH, has partnered with Cisco and NVIDIA to support the establishment of Indonesia’s AI Center of Excellence (CoE). Led by the Ministry of Communications and Digital Affairs, called Komdigi, the CoE aims to advance secure technologies, cultivate local talent and foster innovation through collaboration with startups.
Indosat Ooredoo Hutchison President Director and CEO Vikram Sinha, Cisco Chair and CEO Chuck Robbins and NVIDIA Senior Vice President of Telecom Ronnie Vasishta today detailed the purpose and potential of the CoE during a fireside chat at Indonesia AI Day, a conference focused on how artificial intelligence can fuel the nation’s digital independence and economic growth.
As part of the CoE, a new NVIDIA AI Technology Center will offer research support, NVIDIA Inception program benefits for eligible startups, and NVIDIA Deep Learning Institute training and certification to upskill local talent.
“With the support of global partners, we’re accelerating Indonesia’s path to economic growth by ensuring Indonesians are not just users of AI, but creators and innovators,” Sinha added.
“The AI era demands fundamental architectural shifts and a workforce with digital skills to thrive,” Robbins said. “Together with Indosat, NVIDIA and Komdigi, Cisco will securely power the AI Center of Excellence — enabling innovation and skills development, and accelerating Indonesia’s growth.”
“Democratizing AI is more important than ever,” Vasishta added. “Through the new NVIDIA AI Technology Center, we’re helping Indonesia build a sustainable AI ecosystem that can serve as a model for nations looking to harness AI for innovation and economic growth.”
Making AI More Accessible
The Indonesia AI CoE will comprise an AI factory that features full-stack NVIDIA AI infrastructure — including NVIDIA Blackwell GPUs, NVIDIA Cloud Partner reference architectures and NVIDIA AI Enterprise software — as well as an intelligent security system powered by Cisco.
Called the Sovereign Security Operations Center Cloud Platform, the Cisco-powered system combines AI-based threat detection, localized data control and managed security services for the AI factory.
Building on the sovereign AI initiatives Indonesia’s technology leaders announced with NVIDIA last year, the CoE will bolster the nation’s AI strategy through four core pillars:
Some 28 independent software vendors and startups are already using IOH’s NVIDIA-powered AI infrastructure to develop cutting-edge technologies that can speed and ease workflows across higher education and research, food security, bureaucratic reform, smart cities and mobility, and healthcare.
With Indosat’s coverage across the archipelago, the company can reach hundreds of millions of Bahasa Indonesian speakers with its large language model (LLM)-powered applications.
For example, using Indosat’s Sahabat-AI collection of Bahasa Indonesian LLMs, the Indonesia government and Hippocratic AI are collaborating to develop an AI agent system that provides preventative outreach capabilities, such as helping women subscribers over the age of 50 schedule a mammogram. This can help prevent or combat breast cancer and other health complications across the population.
Separately, Sahabat-AI also enables Indosat’s AI chatbot to answer queries in the Indonesian language for various citizen and resident services. A person could ask about processes for updating their national identification card, as well as about tax rates, payment procedures, deductions and more.
In addition, a government-led forum is developing trustworthy AI frameworks tailored to Indonesian values for the safe, responsible development of artificial intelligence and related policies.
Looking forward, Indosat and NVIDIA plan to deploy AI-RAN technologies that can reach even broader audiences using AI over wireless networks.
Learn more about NVIDIA-powered AI infrastructure for telcos.
AI Research
Silicon Valley eyes a governance-lite gold rush
Andreessen Horowitz has had enough of Delaware and is moving a unit’s incorporation out west
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