AI Research
LG AI Research launches upgraded AI model Exaone Path 2.0 to improve cancer diagnosis, treatment options
Bae Kyung-hoon, head of LG AI Research, speaks at a conference held at LG Science Park in Magok-dong, western Seoul, on July 19, 2023. [LG]
LG AI Research on Wednesday unveiled Exaone Path 2.0, its upgraded artificial intelligence (AI) model designed to enhance cancer diagnosis and drug development. The move aligns with LG Group Chairman Koo Kwang-mo’s vision of making AI and biotechnology core growth engines.
Exaone Path 2.0 learns from higher-quality data than the 1.0 version, which was launched in August last year, according to LG AI Research.
It can precisely analyze and predict not only genetic mutations and expression patterns but also subtle changes in human cells and tissues. The institute says this could enable earlier detection of cancers, forecast disease progression and support new drug discovery and personalized treatments.
A key breakthrough comes from new technology that trains the AI not only on small pathology image patches but also on whole-slide imaging. This pushed genetic mutation prediction accuracy to a globally leading level of 78.4 percent.
LG AI Research expects it will help secure the critical “golden hour” for cancer patients by cutting gene test times from over two weeks to under a minute. The institute also unveiled models tailored to specific diseases, including lung and colorectal cancers.
Dr. Hwang Tae-hyun, an expert in AI-driven research in precision oncology, immuno-oncology, cellular therapy and 3D/4D molecular modeling, is a professor at Vanderbilt University Medical Center. [LG]
LG is bolstering this initiative through a partnership with Dr. Hwang Tae-hyun at Vanderbilt University Medical Center, a leading expert in biomedicine. Hwang, a prominent Korean scientist, heads a U.S. government-backed “Cancer Moonshot” project targeting gastric cancer.
LG AI Research and Hwang’s team plan to jointly build a multimodal medical AI platform that utilizes real clinical tissue samples, pathology images and treatment data from cancer patients in clinical trials. They believe this will usher in an era of personalized, precision medicine.
Their collaboration also underscores Chairman Koo’s push to position AI and bio as technologies that transform customers’ lives. LG AI Research and Hwang’s team see this platform as the world’s first attempt to implement clinical AI in this way.
Starting with oncology, the team will expand into transplant rejection, immunology and diabetes research.
“Our goal isn’t just to develop another AI model. We want to create a platform that actually helps doctors treat patients in real clinical settings,” Hwang said. “This won’t just be a diagnostic tool — it has the potential to become a game changer that transforms the entire process of drug development.”
Performance level of LG AI Research’s precision medical AI model EXAONE Path 2.0 [LG]
Translated from the JoongAng Ilbo using generative AI and edited by Korea JoongAng Daily staff.
BY NA SANG-HYEON [[email protected]]
AI Research
LG AI Research unveils Exaone Path 2.0 to enhance cancer diagnosis and treatment
By Alimat Aliyeva
On Wednesday, LG AI Research unveiled Exaone Path 2.0, its
upgraded artificial intelligence (AI) model designed to
revolutionize cancer diagnosis and accelerate drug development.
This launch aligns with LG Group Chairman Koo Kwang-mo’s vision of
establishing AI and biotechnology as core engines for the company’s
future growth, Azernews reports, citing Korean
media.
According to LG AI Research, Exaone Path 2.0 is trained on
significantly higher-quality data compared to its predecessor,
launched in August last year. The enhanced model can precisely
analyze and predict not only genetic mutations and expression
patterns but also detect subtle changes in human cells and tissues.
This advancement could enable earlier cancer detection, more
accurate disease progression forecasts, and support the development
of new drugs and personalized treatments.
A key breakthrough lies in the new technology that trains the AI
not just on small pathology image patches but also on whole-slide
imaging, pushing genetic mutation prediction accuracy to a
world-leading 78.4 percent.
LG AI Research expects this technology to secure the critical
“golden hour” for cancer patients by slashing gene test turnaround
times from over two weeks to under a minute. The institute also
introduced disease-specific AI models focused on lung and
colorectal cancers.
To strengthen this initiative, LG has partnered with Dr. Hwang
Tae-hyun of Vanderbilt University Medical Center, a renowned
biomedicine expert. Dr. Hwang, a prominent Korean scientist, leads
the U.S. government-supported “Cancer Moonshot” project aimed at
combating gastric cancer.
Together, LG AI Research and Dr. Hwang’s team plan to develop a
multimodal medical AI platform that integrates real clinical tissue
samples, pathology images, and treatment data from cancer patients
enrolled in clinical trials. They believe this collaboration will
usher in a new era of personalized, precision medicine.
This partnership also reflects Chairman Koo’s strategic push to
position AI and biotechnology as transformative technologies that
fundamentally improve people’s lives. LG AI Research and Dr.
Hwang’s team regard their platform as the world’s first attempt to
implement clinical AI at such a comprehensive level.
While oncology is the initial focus, the team plans to expand
the platform’s capabilities into other critical areas such as
transplant rejection, immunology, and diabetes research.
“Our goal isn’t just to develop another AI model,” Dr. Hwang
said. “We want to create a platform that genuinely assists doctors
in real clinical settings. This won’t be merely a diagnostic tool —
it has the potential to become a game changer that transforms the
entire process of drug development.”
AI Research
Global CPG Companies Join Generative and Agentic AI Rush
Consumer packaged goods companies are accelerating the adoption of artificial intelligence in their operations, marketing and supply chains as they seek new ways to boost growth and efficiency in a mature and competitive industry.
AI Research
Senator Wiener Expands AI Bill Into Landmark Transparency Measure Based on Recommendations of Governor’s Working Group
SACRAMENTO – Senator Scott Wiener (D-San Francisco) announced amendments to expand Senate Bill (SB) 53 into a first-in-the-nation transparency requirement for the largest AI companies. The new provisions draw on the recommendations of a working group led by some of the world’s leading AI experts and convened by Governor Newsom. Building on the report’s “trust, but verify” approach, the amended bill requires the largest AI companies to publicly disclose their safety and security protocols and report the most critical safety incidents to the California Attorney General. The requirements codify voluntary agreements made by leading AI developers to boost trust and accountability and establish a level playing field for AI development.
SB 53 retains provisions — called “CalCompute” — that advance a bold industrial strategy to boost AI development and democratize access to the most advanced AI models and tools. CalCompute will be a public cloud compute cluster housed at the University of California that provides free and low-cost access to compute for startups and academic researchers. CalCompute builds on Senator Wiener’s recent legislation to boost semiconductor and other advanced manufacturing in California by streamlining permit approvals for advanced manufacturing plants, and his work to protect democratic access to the internet by authoring the nation’s strongest net neutrality law.
SB 53 also retains its protections of whistleblowers at AI labs who disclose significant risks.
Weeks ago, the U.S. Senate voted 99-1 to remove provisions of President Trump’s “Big Beautiful Bill” that would have prevented states from enacting AI regulations. By boosting transparency, SB 53 builds on this vote for accountability.
“As AI continues its remarkable advancement, it’s critical that lawmakers work with our top AI minds to craft policies that support AI’s huge potential benefits while guarding against material risks,” said Senator Wiener. “Building on the Working Group Report’s recommendations, SB 53 strikes the right balance between boosting innovation and establishing guardrails to support trust, fairness, and accountability in the most remarkable new technology in years. The bill continues to be a work in progress, and I look forward to working with all stakeholders in the coming weeks to refine this proposal into the most scientific and fair law it can be.”
As AI advances, risks and benefits grow
Recent advances in AI have delivered breakthrough benefits across several industries, from accelerating drug discovery and medical diagnostics to improving climate modeling and wildfire prediction. AI systems are revolutionizing education, increasing agricultural productivity, and helping solve complex scientific challenges.
However, the world’s most advanced AI companies and researchers acknowledge that as their models become more powerful, they also pose increasing risks of catastrophic damage. The Working Group report states:
Evidence that foundation models contribute to both chemical, biological, radiological, and nuclear (CBRN) weapons risks for novices and loss of control concerns has grown, even since the release of the draft of this report in March 2025. Frontier AI companies’ [including OpenAI and Anthropic] own reporting reveals concerning capability jumps across threat categories.
To address these risks, AI developers like Meta, Google, OpenAI, and Anthropic have entered voluntary commitments to conduct safety testing and establish robust safety and security protocols. Several California-based frontier AI developers have designed industry-leading safety practices including safety evaluations and cybersecurity protections. SB 53 codifies these voluntary commitments to establish a level playing field and ensure greater accountability across the industry.
Background on the report
Governor Newsom convened the Joint California Policy Working Group on AI Frontier Models in September 2024, following his veto of Senator Wiener’s SB 1047, tasking the group to “help California develop workable guardrails for deploying GenAI, focusing on developing an empirical, science-based trajectory analysis of frontier models and their capabilities and attendant risks.”
The Working Group is led by experts including the “godmother of AI” Dr. Fei-Fei Li, Co-Director of the Stanford Institute for Human-Centered Artificial Intelligence; Dr. Mariano-Florentino Cuéllar, President of the Carnegie Endowment for International Peace; and Dr. Jennifer Tour Chayes, Dean of the UC Berkeley College of Computing, Data Science, and Society.
On June 17, the Working Group released their Final Report. While the report does not endorse specific legislation, it promotes a “trust, but verify” framework to establish guardrails that reduce material risks while supporting continued innovation.
SB 53 balances AI risk with benefits
Drawing on recommendations of the Working Group Report, SB 53:
- Establishes transparency into large companies’ safety and security protocols and risk evaluations. Companies will be required to publish their safety and security protocols and risk evaluations in redacted form to protect intellectual property.
- Mandates reporting of critical safety incidents (e.g., model-enabled CBRN threats, major cyber-attacks, or loss of model control) within 15 days to the Attorney General.
- Protects employees and contractors who reveal evidence of critical risk or violations of the act by AI developers.
The bill’s provisions apply only to a small number of well-resourced companies, and only to the most advanced models. The Attorney General has the power to update the thresholds governing which companies are covered under the bill to ensure the requirements keep up with rapid advancements in the field, but must cover only well-resourced companies at the frontier of AI development.
Under SB 53, the Attorney General imposes civil penalties for violations of the act. SB 53 does not impose any new liability for harms caused by AI systems.
In addition, SB 53 creates CalCompute, a research cluster to support startups and researchers developing large-scale AI. The bill helps California secure its global leadership as states like New York establish their own AI research clusters.
SB 53 is sponsored by the Encode AI, Economic Security Action California, and the Secure AI Project.
SB 53 is supported by a broad coalition of researchers, industry leaders, and civil society advocates:
“California has long been the birthplace of major tech innovations. SB 53 will help keep it that way by ensuring AI developers responsibly build frontier AI models,” said Sneha Revanur, president and founder of Encode AI, a co-sponsor of the bill. “This bill reflects a common-sense consensus on AI development, promoting transparency around companies’ safety and security practices.”
“At Elicit, we build AI systems that help researchers make evidence-based decisions by analyzing thousands of academic papers,” said Andreas Stuhlmüller, CEO of Elicit. “This work has taught me that transparency is essential for AI systems that people rely on for critical decisions. SB53’s requirements for safety protocols and transparency reports are exactly what we need as AI becomes more powerful and widespread. As someone who’s spent years thinking about how AI can augment human reasoning, I believe this legislation will accelerate responsible innovation by creating clear standards that make future technology more trustworthy.”
“I have devoted my life to advancing the field of AI, but in recent years it has become clear that the risks it poses could threaten us all,” said Geoffrey Hinton, University of Toronto Professor Emeritus, Turing Award winner, Nobel laureate, and a “godfather of AI.” “Greater transparency requirements into how companies are addressing safety concerns from the most powerful technology of our time is an important step towards addressing those risks.”
“SB 53 is a smart, targeted step forward on AI safety, security, and transparency,” said Bruce Reed, Head of AI at Common Sense Media. “We thank Senator Wiener for reinforcing California’s strong commitment to innovation and accountability.”
“AI can bring tremendous benefits, but only if we steer it wisely. Recent evidence shows that frontier AI systems can resort to deceptive behavior like blackmail and cheating to avoid being shut down or fulfill other objectives,” said Yoshua Bengio, Full Professor at Université de Montréal, Co-President and Scientific Director of LawZero, Turing Award winner and a “godfather of AI.” “These risks must be taken with the utmost seriousness alongside other existing and emerging threats. By advancing SB 53, California is uniquely positioned to continue supporting cutting-edge AI while proactively taking a step towards addressing these severe and potentially irreversible harms.”
“Including safety and transparency protections recommended by Gov. Newsom’s AI commission in SB 53 is an opportunity for California to be on the right side of history and advance commonsense AI regulations while our national leaders dither,” said Teri Olle, Director of Economic Security California Action, a co-sponsor of the bill. “In addition to making sure AI is safe, the bill would create a public option for cloud computing – the critical infrastructure necessary to fuel innovation and research. CalCompute would democratize access to this powerful resource that is currently enjoyed by a tiny handful of wealthy tech companies, and ensure that AI benefits the public. With inaction from the federal government – and on the heels of the defeat of the proposed 10-year moratorium on AI regulations – California should act now and get this done.”
“The California Report on Frontier AI Policy underscored the growing consensus for the importance of transparency into the safety practices of the largest AI developers,” said Thomas Woodside, Co-Founder and Senior Policy Advisor, Secure AI Project, a co-sponsor of the bill. “SB 53 ensures exactly that: visibility into how AI developers are keeping their AI systems secure and Californians safe.”
“Reasonable people can disagree about many aspects of AI policy, but one thing is clear: reporting requirements and whistleblower protections like those in SB 53 are sensible steps to provide transparency, inform the public, and deter egregious practices without interfering with innovation,” said Steve Newman, Technical co-founder of eight technology startups, including Writely – which became Google Docs, and co-creator of Spectre, one of the most influential video games of the 1990s.
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